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Development of Arginine Stearate-Based Solid Lipid Nanoparticles for Enhanced Idebenone Delivery: In Vitro Evaluation on Glioblastoma Model.

Authors: Petralito S, Curcio F, Di Muzio L, Sole R, Giordano F, Leonetti AE, Trombino S, Cassano R

Molecules (Basel, Switzerland)

Acute coronary syndrome (ACS) is classically attributed to plaque rupture. However, plaque erosion is now recognized as an equally important mechanism, accounting for up to 40% of ACS cases. It is mor...

depression treatment mental health open access

Vegetation transpiration contributions to precipitation recycling in a semi-arid grassland: an isotope-constrained source partitioning framework.

Authors: Guo S, Jia D, Ji M, Wang R, Zhang D

Frontiers in plant science

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor, classified as a grade IV astrocytoma by the World Health Organization (WHO) []. Originating from glial cells, which...

depression treatment mental health open access

Altered Glymphatic-Related MRI Metrics and Brain Network Reorganization in Drug-Naive Children With Self-Limited Epilepsy With Centrotemporal Spikes.

Authors: Luo Y, Zhou X, Xu J, Lai H, Lei Q, Chen Y, Liu H

CNS neuroscience & therapeutics

Repeated sprint ability (RSA) is a fundamental determinant of performance in many intermittent sports, including football, rugby, hockey and basketball. Where decisive moments frequently require athle...

depression treatment mental health open access

Youth-associated protein TIMP2 regulates microglial state and function in healthy and aged mice.

Authors: Hemmer BM, Philippi SM, Ferreira AC, Petridis SF, Phan A, Castellano JM

Nature communications

Ulcerative colitis‐associated neoplasia (UCAN), which includes both dysplasia and colitis‐associated colorectal carcinoma, remains a major complication of long‐standing ulcerative colitis [, ]. Endosc...

depression treatment mental health open access

Effects of Acute Caffeine Ingestion on Morning Strength, Power and Repeated Sprint Measures in Males: A Standardized Approach.

Authors: Vickery SJ, Giacomoni M, Agulhari JPS, Batten T, Crozier OG, Goorwappa D, Mauvieux B, Pullinger SA, Chester N, Hesketh SJ, Edwards BJ

Nutrients

The persistent challenge of paraffin wax deposition within crude oil production and transportation infrastructure represents a critical operational bottleneck in the petroleum industry worldwide. As c...

depression treatment mental health open access

Infraorbital Paresthesia as a Potential Indication for Reconstruction of Pure Blowout Orbital Fractures: A Case Report.

Authors: Al-Shayyab MH, Dahooh A, Alahmad H, Barakat M, Abdallah S, Ghattas L, U Wais MY

Case reports in dentistry

Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus and remains a leading cause of visual impairment and blindness among working-age adults worldwide (...

depression treatment mental health open access

Intermittent Theta Burst Stimulation Improves Sleep in Autism Spectrum Disorder by Reorganizing Overlapping Brain Networks With Neurochemical and Transcriptomic Signatures: A Randomized Controlled Tri

Authors: Zhang H, Xiong B, Liu H, Huang Y, Zhang J, Yu R, Jiang W, She T

CNS neuroscience & therapeutics

Prehabilitation has emerged over the last decade as an essential component of perioperative care in patients undergoing colorectal surgery. Defined as a preoperative multimodal intervention combining...

depression treatment mental health open access

Discordance between in vitro susceptibility and clinical response in early-onset neonatal sepsis caused by Morganella morganii: a case report in an extremely preterm infant.

Authors: Omari EAS, Albow YK, Imad Iwaiwi B, Abuawwad M

Frontiers in pediatrics

Diabetes is a major and rapidly growing global health issue, which is accompanied by a range of micro and macrovascular comorbidities that significantly impact mortality and healthcare costs. Several...

depression treatment mental health open access

Sustained benefit of compression therapy for preventing recurrent leg cellulitis: extended follow-up of a randomised controlled trial.

Authors: Webb E, Neeman T, Bowden FJ, Gaida J, Mumford V, Bissett B

EClinicalMedicine

Bronchoscopy is widely used for diagnosing and treating lung diseases due to its convenience and efficiency. However, the procedure is invasive, may cause hypoxemia, and often results in significant p...

depression treatment mental health open access

Call to action: identifying an underlying bleeding disorder in adolescents with heavy menstrual bleeding.

Authors: Gupta S, Castaman G, Funkhouser K, Lewandowska M, Weyand AC, Di Michele S, Fulghesu AM, Gaudreau H, Shapiro AD

Research and practice in thrombosis and haemostasis

We evaluated whether hypertriglyceridemia predicts outcome in acute ischemic stroke patients treated with mechanical thrombectomy at the Comprehensive Stroke Centre. Among patients with large-vessel d...

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From (18)F‑MC225 to Conformationally Free Derivatives.

Authors: Lisi AT, Mastropasqua F, Abate C, Contino M, Perrone MG, Graziano G, Carrieri A, Colabufo NA, Filosa C, Calcagni ML, Giordano A, Di Giuda D

ACS omega

Among the various currently available additive manufacturing (AM) methods, fused deposition modelling (FDM) dominates both desktop and industrial-scale polymer printing, primarily due to its low capit...

depression treatment mental health open access

Acute diquat poisoning in children: a single-center retrospective observational study.

Authors: Li M, Jia P, Wei E

Frontiers in pediatrics

Drought stands out as a major bottleneck to agricultural productivity, quality, and global food security, disrupting morphological, physiological, and biochemical processes, adversely affecting growth...

depression treatment mental health open access

Pharmacokinetics, safety, and pharmacodynamics of intravenous methoxyethyl etomidate hydrochloride (ET-26-HCl) in Chinese participants with hepatic impairment.

Authors: Hu Y, Zheng W, Zhang H, Li L, Diao L, Yang X, Ding Y

Frontiers in pharmacology

Gastric cancer (GC) originates from gastric epithelial cells. As of 2022, gastric cancer ranked fifth worldwide in both incidence and mortality among malignant tumors, with approximately 970,000 new c...

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Obesity-driven low-grade chronic inflammation as a mechanistic bridge to chronic pain: from adipose tissue remodeling to central sensitization.

Authors: Ma YX, Lin M, Nan Y, Li NN, Liu B, Wang HR, Ning SY, Zhang Z

Frontiers in immunology

Indoor mobility is a fundamental indicator of functional status, health, and well-being in older adults. Community-dwelling seniors spend approximately 83% of their time at home [], significantly more...

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Toward an Equity-Based Response to Endometriosis.

Authors: Cordova-Gomez A, Mburu G, Mecha EO, Candau Y, Gonsalves L, Allotey P

Women's health reports (New Rochelle, N.Y.)

Physical exercise has played a central role in human health since early civilization. Evidence from 3000 BCE indicates that nomadic societies relied on movement for survival, and over time, activity e...

depression treatment mental health open access