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Showing 15 of 20167 papers

Transplantation as disease modifying therapy in the era of gene therapy medicinal products - health policy considerations.

Authors: Wagenmakers M, Lehman A, Hoed CD, Dussen LV, Langeveld M, Sirrs S

Orphanet journal of rare diseases

Transplantation in patients with inherited metabolic diseases [IMDs] can be used as supportive therapy or as disease modifying therapy to alter the disease course or even provide cure. Data have sugge...

anxiety disorders mental health open access

Application of Swietenia macrophylla Polymer/Nanocomposites for Mitigating Paraffin Wax Deposition.

Authors: Aji A, Mohyaldinn ME, Ben Mahmud HK, Abduljabbar A, Hussein IA

Polymers

Maple syrup urine disease (MSUD) is a rare, autosomal recessive, inherited disorder, caused by biallelic mutations in the , , , or genes []. The estimated incidence of MSUD is 1 per 185,000 live birt...

depression treatment mental health open access

Plant Polysaccharides in Alzheimer's Disease: From Phytochemistry to Microbiota-Gut-Brain Axis Mechanisms-Resolving the Pharmacokinetic-Pharmacodynamic Paradox.

Authors: Gao J, Li L, Liu Q, Zhang N, Li Y

Molecules (Basel, Switzerland)

The orbit is the bony vault that houses the eyeball, but this vault is very thin in specific areas, especially the floor and the medial wall, which are commonly fractured following blunt trauma to the...

depression treatment mental health open access

A Unified Temperature-Dependent Elastoplastic Damage Framework for Concrete from Sub-Zero to Elevated Temperatures.

Authors: Gao P, You Q, Xie J, Du X, Pan Y, Lu B, Chang L

Materials (Basel, Switzerland)

Monitoring uterine contractility is crucial in obstetrics for assessing labor progression, diagnosing preterm labor risk, and guiding interventions. Traditionally, uterine activity has been monitored...

depression treatment mental health open access

Symptomatic Management of Sudden Unilateral Severe Spasticity Following a Fall in a Patient With Traumatic Spinal Cord Injury: A Case Report-From Etiology To Symptom-Focused.

Authors: Dong J, Li Y, Han Y, Zhang F, Li S, Jin L

Clinical case reports

Autism spectrum disorder (ASD) remains a major challenge for therapeutic development due to its complex neurobiological underpinnings and heterogeneous clinical presentation. Increasing evidence indic...

depression treatment mental health open access

Clinical study of remimazolam combined with ultrasound-guided superior laryngeal nerve block in elderly patients with coronary heart disease undergoing bronchoscopy.

Authors: Sang Y, Wu Y, Bai H, Yang L

Frontiers in medicine

Dietary supplement use is common among athletes across different sports and performance levels, with studies indicating that approximately 40–90% of athletes report using dietary supplements [,,]. The...

depression treatment mental health open access

Association between obstructive sleep apnea syndrome and the risk of diabetic retinopathy: a meta-analysis of cohort studies.

Authors: Zhou Y, Dai R, Chen Y, Chen Z

Frontiers in endocrinology

Veterinary healthcare remains underserved compared to human healthcare due to fragmented data repositories, limited centralized clinical datasets, reduced access to specialized veterinary services in...

depression treatment mental health open access

From subjective assessment to data-driven diagnosis: the AI revolution in multimodal early detection of Sjögren's disease.

Authors: Zhou Y, Yu B, Chang R, Ding Y, Wang Y, Han M

Frontiers in immunology

Cardiovascular diseases and type 2 diabetes remain leading global causes of morbidity and mortality. Cardiovascular diseases alone account for more than 17 million deaths annually []. Traditional risk...

depression treatment mental health open access

Crystal Violet Staining for Colitis-associated Neoplasia-guided Delineation of Ulcerative Colitis-associated Neoplasia for Endoscopic Submucosal Dissection: A Four-case Report.

Authors: Tomioka A, Chiya N, Hokari R, Ryozawa S

DEN open

Concrete is the most widely used structural material in civil and protective engineering, and its service environments are increasingly extending toward both ends of the extreme-temperature spectrum....

depression treatment mental health open access

Current Evidence and Practical Considerations for Adaptogen Use in Exercise Recovery, Training Adaptation, and Exercise Performance in Athletes: A Narrative Review.

Authors: Książek A

Nutrients

The last decade has seen rapid advances in NIPT. Because of the robust performance characteristics of NIPT, it has been widely applied for prenatal screening of fetal trisomy 21, 18 and 13 []. With an...

depression treatment mental health open access

Astragaloside IV suppresses triple-negative breast cancer cell migration and invasion by targeting BCAT1-mediated branched-chain amino acid metabolism.

Authors: Liu YT, Zhang L, Sun XD

Oncology letters

For decades, psoriasis has been recognized as a disease associated with systemic manifestations beyond the skin, including in the cardiovascular system. Until now it has been proven in clinical studie...

depression treatment mental health open access

Upper-Limb Paresis Severity Is Associated With Practice Dosage During Task-Oriented Training in Subacute Stroke-An Exploratory Secondary Analysis.

Authors: Durairaj S, Jagadish A, Solomon JM, Levin MF

Physiotherapy research international : the journal for researchers and clinicians in physical therapy

Aging is accompanied by progressive functional decline across multiple organ systems, but its impact on the brain is especially devastating, given the dysfunction wrought across key cognitive domains...

depression treatment mental health open access

Macroscopic evidence of a platelet-rich thrombus in a diabetic patient with non-ST-elevation myocardial infarction.

Authors: Brania P, Furtak K, Tarnowski M, Domoń D, Wałcerz-Bajorska M, Gorczyca-Głowacka I

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Breech is one of the most common abnormal fetal positions in obstetrics. The incidence of breech during full-term pregnancy is 3%-4% []. Natural delivery in breech has a high risk of fetal asphyxia an...

depression treatment mental health open access

Precision diagnostics in bronchiectasis: current advances in imaging, microbiology, biomarkers, and digital health.

Authors: Wu B, Lu S, Liu H

Frontiers in medicine

Patients who have experienced traumatic spinal cord injury (TSCI) may develop various comorbidities and secondary health conditions [], among which spasticity is the most prevalent []. Spasticity, inc...

depression treatment mental health open access

The use of the Edmonton Obesity Staging System compared to body mass index to predict adverse pregnancy outcomes.

Authors: White SE, Stamilio DM

Pregnancy (Hoboken, N.J.)

Temporomandibular disorders (TMDs) are clinical conditions that affect the temporomandibular joint (TMJ), masticatory muscle, and ligaments. TMD is a functional disorder that can afflict up to 60% of...

depression treatment mental health open access