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The Influence of Hydroxyl Group on Nerve Excitability Blockade by Limonene and Its Hydroxylated Metabolites, Perillyl Alcohol and Carveol.

Authors: Amâncio LC, Sousa-Silva E, Cardeal-Dos-Santos AN, Rabelo ISM, Saraiva GPA, Cardoso-Teixeira AC, Moreira-Gomes MD, Cruz Freire JED, Coelho-de-Souza AN, Ferreira-da-Silva FW, Silva-Alves KSD, Leal-Cardoso JH

Molecules (Basel, Switzerland)

Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus, and has become the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide....

depression treatment mental health open access

Synergistic Optimisation of Surface Properties and Surface Quality of FDM ABS Specimens Based on RSM and CWOA.

Authors: Zhao J, Zhu R, Ma H, Li X, Yang L, Li P, Wang S, Wei T

Polymers

Upper gastrointestinal endoscopy is indispensable for the diagnosis and treatment of not only malignant tumors such as gastric cancer, esophageal cancer, and duodenal tumors, but also peptic ulcer dis...

depression treatment mental health open access

Biological Profile of Ferulic Acid-Based Thiazolidin-4-One Derivatives: Toxicity, Inflammation, and Oxidative Stress Biomarkers.

Authors: Dragan M, Iacob AT, Mircea C, Stan CD, Dragostin OM, Focșa AV, Tatarciuc D, Stan RT, Poroch M, Profire L

Molecules (Basel, Switzerland)

India is undergoing accelerated population aging, with a substantial rise in the proportion of individuals aged over 65 years []. This demographic transition is accompanied by a rise in the prevalence...

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Machine learning and deep learning for diagnosis of Polyendocrine Metabolic Ovarian Syndrome: systematic review and meta-analysis.

Authors: Fan H, Chen S, Cai F, Tang C, Chen X, Chen J, Wu P

Frontiers in endocrinology

Liquid chromatography—including thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC/LC)—and gas chromatography (GC) are fundamental separation techniques in analytical che...

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Bicruciate ligament avulsions, lateral meniscus dual root avulsions - "Tibial Avulsion Tetrad"- with menisco- capsular injury - Floating meniscus in innocuous looking proximal tibia fracture.

Authors: Kembhavi R, Chitten JJ, Parmeshwar SS

Journal of orthopaedic case reports

Calvarial thinning refers to progressive loss of thickness of the upper, dome-shaped portion of the skull, including the frontal, parietal, and occipital bones. Calvarial thinning may arise from conge...

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Cathetus yuanjiangensis (Phyllanthaceae, Phyllantheae), a New Species from Southwest China, with a New Combination and an Updated Key to C. Subgen. Cathetus.

Authors: Yang F, Chen C, Li Z, Wu JY, Fan H, Wang HC

Plants (Basel, Switzerland)

As the first quarter of the 21st century concludes, an artificial intelligence (AI) revolution has significantly impacted various sectors, including healthcare. The main applications of AI software in...

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Bidirectional regulation between mitochondrial metabolic reprogramming and epigenetic modifications in renal tubular epithelial cell injury of diabetic kidney disease.

Authors: Wu G, Chen F, Xiong Q

Frontiers in endocrinology

Obesity has become one of the most challenging non-communicable diseases of the 21st century. A pooled analysis of 3–663 population-representative surveys covering 222 million children, adolescents, a...

depression treatment mental health open access

Idiopathic calvarial thinning mimicking en coup de sabre deformity.

Authors: Joerg L, Schwartz J

JAAD case reports

The placebo effect is a positive outcome resulting from the belief of having received a beneficial treatment or condition, such as the belief that one has ingested caffeine to enhance sports performan...

depression treatment mental health open access

Comparative Electrocorticographic Signatures of S‑Ketamine and Racemic Ketamine in the Rat Visual Cortex Across Temporal Phases.

Authors: Lins A, Eiró-Quirino L, de Souza LV, Bittencourt DR, Duarte LC, de Andrade Junior LFD, Cardoso EA, Farias RAF, Hayasaki NDC, da Silva FW, Silva HQ, Lopes DB, Lopes AE, Hamoy M

ACS omega

Etomidate, a γ-aminobutyric acid type A receptor agonist, is a hypnotic that is used to induce anaesthesia and is well known for its remarkably stable cardiorespiratory profile (; ; ). However, the us...

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Indoor Mobility Patterns Measured by PIR Sensors for Classifying Health-Related Quality of Life in Older Adults Using Machine Learning.

Authors: Cruz DR, Belmar AL, Fleury A, Lam M, Maidana JP, Toro CT

Sensors (Basel, Switzerland)

Endometriosis affects 190 million, or 1 in 10, women worldwide. It is a complex chronic condition with an impact extending from menarche through menopause, causing chronic pain during menstruation and...

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Using Negative Control Outcomes to Detect Selection Bias in Mendelian Randomization Studies.

Authors: Gkatzionis A, Smith GD, Tilling K

Statistics in medicine

Frailty is a multidimensional syndrome characterised by reduced physiological reserve and increased vulnerability to stressors, predisposing individuals to adverse clinical outcomes []. In patients wi...

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Real-world Effectiveness and Safety of Lebrikizumab in Atopic Dermatitis: A TREATgermany Analysis.

Authors: Kind B, Pham C, Heinrich L, Honstein T, Heratizadeh A, Harder I, Stölzl D, Staubach-Renz P, Schaefer T, Abraham S, Augustin M, Ramaker-Brunke J, Pinter A, Meinhardt K, Quist S, Anders S, Schwarz B, Schulz-Kiesow M, Steinke S, Adler N, Handrick C, Schaekel K, Sticherling M, Bong A, Jacobs FD, Großmann B, Stahl M, Buerkle CP, Gorriahn-Maiterth HL, Biedermann T, Schmitt J, Weidinger S, Werfel T

Acta dermato-venereologica

The tribe Phyllantheae is the largest tribe in the family Phyllanthaceae, comprising more than 1200 species []. The systematic classification of this tribe has long been plagued by the paraphyly of s...

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Bilayer Scaffold for Corneal Stromal Engineering: Solvent-Cast Polyvinyl Alcohol/Sodium Alginate and Electrospun Aligned Polycaprolactone Fibers.

Authors: Orash Mahmoudsalehi A, Rios KSC, Guerrero-Beltrán CE, Ortega-Lara W

Polymers

Ulcerative colitis (UC) is characterized by persistent inflammation of the colonic mucosa []. Epidemiological data indicate that UC has its highest prevalence in Western industrialized countries, part...

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Recent advances, comparative performance, and data requirements of artificial intelligence-assisted technologies for the diagnosis of gastric cancer.

Authors: Zhang Z, Liu Z, Zhang X, Lv K, Huang Y, Zheng C, He T

Frontiers in gastroenterology (Lausanne, Switzerland)

Ketamine (CHClNO) is a phencyclidine-derived dissociative anesthetic composed of two enantiomers, -ketamine (KS) and -ketamine (KR). These molecules differ markedly in their pharmacodynamic properties...

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Impact of AI-Augmented informed consent on preoperative anxiety and patient understanding: A prospective Observational Study.

Authors: Aydın YM, Özarslan TE, Girgin R, Demirkıran ED, Akduman B, Mungan NA

Digital health

Skin diseases represent one of the most prevalent and socially disruptive global health burdens, affecting billions of individuals across all age groups and geographical regions. Current epidemiologic...

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