Sustained benefit of compression therapy for preventing recurrent leg cellulitis: extended follow-up of a randomised controlled trial.

Bronchoscopy is widely used for diagnosing and treating lung diseases due to its convenience and efficiency. However, the procedure is invasive, may cause hypoxemia, and often results in significant patient discomfort. As the population ages, more elderly patients with coronary heart disease are undergoing bronchoscopy. This group is more susceptible to hemodynamic fluctuations, which can cause cardiac and cerebral ischemia and hypoxia, increasing perioperative cardiovascular and cerebrovascular risk. Additionally, elderly patients often experience cognitive decline, slower recovery, and more complications postoperatively. Remimazolam takes effect rapidly, is rapidly metabolized, and has minimal effects on respiratory and circulatory functions, making it particularly suitable for elderly patients (, ). Ultrasound-guided superior laryngeal nerve block (SLNB) can precisely block sensation in the larynx, effectively suppressing the gag reflex (). In addition, SLNB may reduce sedative and opioid requirements and contribute to improved hemodynamic stability. To date, no reports have described the combined use of these two techniques during bronchoscopy in elderly patients with coronary heart disease. This study aimed to investigate the efficacy and safety of this combination regimen to provide clinicians with an optimized anesthesia strategy. The Ethics Committee of the First Hospital of Shanxi Medical University approved this study on January 21, 2025 (No. KYLL-2025-002). All procedures followed the institution’s Research Ethics Committee standards and the Declaration of Helsinki. The study was registered with the China Clinical Trials Registry (ChiCTR2600121168). Investigators explained the study to all subjects, who then signed informed consent forms.