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Showing 15 of 20167 papers

Distinct contributions of mu opioid and CB2 cannabinoid receptors to neuroimmune and behavioral responses.

Authors: Kibret B, Onaivi ES, Sharma V

Advances in drug and alcohol research

Atrial fibrillation (AF) is one of the most common arrhythmias in adults and one of the most prevalent heart rhythm disorders (; ). Given its rising prevalence and increasing incidence with advancing...

anxiety disorders mental health open access

DNMT1 as an environmental sensor: epigenetic pathways linking environmental exposures, sex hormone signaling, and vulnerability to neurodevelopmental and neurodegenerative diseases.

Authors: Vöhringer K, Müller MS, Yildiz CB, Zimmer-Bensch G

Frontiers in neurology

The developing and adult brain relies on a dynamic interplay between intrinsic genetic programs and extrinsic environmental signals to build and maintain complex neural circuits (). Epigenetic mechani...

anxiety disorders mental health open access

Emotional pain in non-human mammals: from neural circuitry and opioid signaling to dysthymia-like states, grief-like behaviors, and physiological dysregulation.

Authors: Mota-Rojas D, Whittaker AL, Coria-Avila GA, Hernández-Avalos I, Martínez-Burnes J, Domínguez-Oliva A, Olmos-Hernández A, Torres-Bernal F, Reyes-Sotelo B, Miranda-Cortes A, Casas-Alvarado A, Grandin T

Frontiers in veterinary science

Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), remains one of the most serious and potentially life-threatening complications following orthopedic t...

anxiety disorders mental health open access

A study of the association between the early pregnancy thrombosis-thyroid axis and pregnancy outcomes in patients with recurrent spontaneous abortion.

Authors: Wang Y, Zhao J, Li G, Zheng S, Wang C, Sang C, Han Q, Li M, He J

Frontiers in endocrinology

Skin injury is a key clinical issue, especially chronic wounds, such as diabetic ulcers [, , ], infected trauma [, , ], burn damage [, , ], radiation-induced skin injuries [, , ], and compromised skin...

anxiety disorders mental health open access

Single-Cell Profiling Reveals a Protective WNT5A-ATF3-FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia.

Authors: Luo R, Fang K, Zhao C, Xiong J, Zhu Y, Lu M, Yan H, Li Z, Wu B, Jiang H, Li Y

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

One common long-term degenerative joint condition is osteoarthritis (OA). OA is predicted to impact 355 million people globally by 2024, and its incidence will continue to climb every year. Osteoarthr...

anxiety disorders mental health open access

A qualitative study exploring postpartum patients' experiences with remote blood pressure monitoring.

Authors: Thatipelli S, Pestka DL, Honeyfield K, Hansen S, Rizvi R, Melton GB, Sabol BA

Pregnancy (Hoboken, N.J.)

Lactate was long considered merely a waste product of metabolism and its presence only viewed as a hallmark of incomplete respiration and oxygen deprivation. This view drastically changed when the abi...

anxiety disorders mental health open access

Post-surgical Pyoderma Gangrenosum Following Elective Aesthetic Procedures: A Case Series of 10 Patients and a Multidisciplinary Treatment Approach.

Authors: Birck MS, Padilha DZ, Borges VPB, Bevilaqua M, Bonamigo RR

Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India

Parkinson's disease (PD), one of the most prevalent neurodegenerative disorders worldwide, is clinically characterized by progressive motor symptoms of bradykinesia, rigidity, resting tremor, and post...

anxiety disorders mental health open access

Targeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in rats.

Authors: Lin J, Wu J, Wang Y, Huo Y, Zhang J

iScience

Tinnitus refers to the perception of sound in the absence of an external acoustic source. It affects approximately 14% of the global adult population, with 20% of affected individuals experiencing com...

anxiety disorders mental health open access

Rhynchophylline rewires DLAT lipoylation via conformational control to reverse mitochondrial bioenergetic collapse against dopaminergic neuronal injury.

Authors: Liang X, Yang X, Wang S, Zhuo F, Hou X, Tu P, Liu Y, Zeng K, Zhang Q

Acta pharmaceutica Sinica. B

Prostate cancer (PC) is one of the most common malignancies of the genitourinary system in older men and has become a major public health concern affecting men’s health worldwide. Projections suggest...

anxiety disorders mental health open access

Unique Anatomical Imaging Findings in Patients With Patulous Eustachian Tube.

Authors: Prabhakar AR, Mehdi Z, Varghese JR, Powell K, Paderin D, Dhanda A, Vazquez SG, Lin KF, Vrabec JT

Laryngoscope investigative otolaryngology

Approximately 40%–85% of individuals with Parkinson's disease (PD) experience pain that negatively affects their quality of life , . Despite the prevalence and burden on daily living, pain in PD is of...

anxiety disorders mental health open access

Noninvasive malaria detection beyond blood sampling.

Authors: Hong SG, Leem JW, Sakthivel H, Kwon S, Park SM, Dewan A, Botana DJ, Kim YL

Sensors & diagnostics

Early detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is well established as a critical factor in reducing morbidity and mortality, and in improving lo...

anxiety disorders mental health open access

Identification of TIMP1 as a Key Regulator of Ferroptosis in Ulcerative Colitis Through Bioinformatics and Functional Experiments.

Authors: Zhou X, Qiao Q, Yang J, Tu H

Gastroenterology research and practice

Mild Cognitive Impairment (MCI) represents a clinical condition of increasing epidemiological relevance, defined by a cognitive decline that exceeds what is expected for the patient’s age and educatio...

anxiety disorders mental health open access

The characterization of Parkinson's disease related pain based on the classification system: The severity of neuropathic pain and the clinical profile of nociplastic pain.

Authors: Tezuka T, Nukariya T, Okusa S, Ueda R, Saegusa H, Okochi R, Sakai Y, Nihei Y, Nakahara J, Seki M

Clinical parkinsonism & related disorders

Migraine is a complex neurological condition characterized by recurrent headache attacks, autonomic and sensory disturbances, and, in approximately one-third of cases, reversible localized neurologica...

anxiety disorders mental health open access

Post Hoc Analyses of A-SURE and PREVENT Confirm the Effectiveness of rFVIIIFc Prophylaxis Across All Ages, BMIs, Severities, and Inhibitor Histories.

Authors: Oldenburg J, Tiede A, Alamelu J, Álvarez Román MT, Bidlingmaier C, Holme PA, Peyvandi F, Bednar E, Nüesch E, Lethagen S

TH open : companion journal to thrombosis and haemostasis

Approximately 70 million people worldwide live with epilepsy, with around 80% of them residing in low- and middle-income countries (LMICs). In Brazil, the prevalence rates range from 9.2 to 18.6 per...

anxiety disorders mental health open access

Does Folic Acid Intake Play Role as a Potential Indicator of Modifiable Maternal Risk Factors in Preconception Period?: A Cross-Sectional Study.

Authors: Hwang DW, Chun KC, Kim YA, Koh JW, Han JY

Women's health reports (New Rochelle, N.Y.)

Pulmonary embolism (PE) constitutes one of the most common manifestations of venous thromboembolism, with substantial morbidity and mortality []. Specifically, based on a large epidemiological analysi...

anxiety disorders mental health open access