Authors: Al-Saadi RS, Luo J, Nichitean AM, Wagner NR, Gaytan NG, Portman DS, Hall SE
G3 (Bethesda, Md.)
Gene set interpretation is a fundamental task in functional genomics, where researchers must derive biological insights from lists of genes identified in high-throughput experiments. Current approache...
Authors: Shalash A, Schumacher-Schuh AF, Salama M, Noyce A, Ha ULN, Chew Seng Tan L, Tanner CM
Journal of Parkinson's disease
AD病理机制复杂，涉及Aβ斑块沉积、τ蛋白过度磷酸化形成的神经原纤维缠结、神经炎症及突触功能障碍等多种病理过程。AD的发病机制尚未完全阐明，Aβ假说是目前主流的假说之一，该假说认为Aβ生成和清除失衡是AD病理的始...
Authors: Prince T, Boyes A, Crethar M, Driver C, Mills L, Hermens DF
Journal of adolescence
AD是一种神经退行性疾病，患者早期表现为记忆力减退，逐渐发展为以计算力、定向力、语言等功能减退的弥散性皮质功能损伤，晚期可出现精神症状并影响生活质量，给社会和医疗保健系统带来沉重的负担。目前临床常规使用...
Authors: Sercu L, Nijlen DV
Journal of adolescence
Elevated irritability is characterized by a heightened proneness to anger and frustration relative to peers (). While irritability exists on a developmentally typical: clinically impairing spectrum, e...
Authors: Bouwman I, Claassen T, Chase MJ, Landen K, Huijbregts MAJ, Tucker MA
The Journal of animal ecology
A multi-faceted behaviour-change strategy achieved consistent, long-term adoption of nurse-initiated care across diverse emergency settings despite political and unexpected challenges. Clinical champi...
Authors: Aggarwal A, Baker HA, Dürst CD, Chen IW, de Chambrier P, Stine C, Gonzales JM, Marvin JS, Vandal M, Lundberg T, Brown-Panton CA, Sakoi K, Patel R, Wang CY, Visser F, Fouad Y, Sunil S, Wiens M, Terai T, Takahashi-Yamashiro K, Thompson RJ, Brown TA, Nasu Y, Nguyen MD, Gordon GRJ, McFarlane S, Podgorski K, Holtmaat A, Campbell RE, Lohman AW
Nature communications
In an ideal situation, we could recognize climate change mitigation measures, or their combinations, that are effective, ethically good and widely supported. However, effective measures that significa...
Authors: Berny LM, Hennessy EA, Finch AJ, Tanner-Smith EE
Drug and alcohol dependence
Qualitative research is increasingly conducted with randomized controlled trials (RCTs) to provide insights into stakeholders’ perceptions and experiences, as well as contextual factors influencing th...
Authors: Calaresi D, Saladino V, Giordano F, Verrastro V
Journal of clinical psychology
Bacterial symbionts are ubiquitous across the animal tree of life (McFall‐Ngai et al., ), and both beneficial (mutualistic) and harmful (pathogenic and parasitic) symbionts significantly impact the ec...
Authors: Yeo D, Kim K, Kim J, Lee S, Lee H, Branda F, Rahmati M, Kim S, Woo HG, Woo S, Hwang Y, Yon DK
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Authors: Zaniewska M
Pharmacological reports : PR
Freshwater ecosystems are among the most threatened habitats globally and continue to degrade rapidly (Albert et al., ). Rivers and lakes provide essential ecosystem services including water supply, f...
Authors: Blawas AM, Fahlbusch J, Barkowski J, Cade DE, Calambokidis J, Friedlaender AS, Southall B, Ponganis PJ, Goldbogen JA
Proceedings of the National Academy of Sciences of the United States of America
The rapid advancement of information and communication technologies has profoundly influenced individuals’ behaviours and habits across all areas of life (OECD, ). Today, technology has become an indi...
Authors: Zhang X, Wu D, Clark WAV
Proceedings of the National Academy of Sciences of the United States of America
Emergency departments (EDs) serve as a primary point of access to health care for many patients seeking care, including for non-urgent administrative and informational needs []. Within many communitie...
Authors: Pajot M, Morfoisse T, Sablé-Meyer M, Lakretz Y, Dehaene S
PLoS computational biology
Myotonic dystrophy type 1 (DM1) is an autosomal dominant neuromuscular disease caused by a CTG repeat expansion within the gene. DM1 is characterized by progressive muscle weakness and myotonia, acco...
Authors: Sánchez Valverde A, Abarca Dotor R, Lopez Muley C, Samaniego Vasquez XS, Parellada Esquius N
Anales del sistema sanitario de Navarra
The fear of falling behind can produce a rat race in the adoption of performance-enhancing technologies: As use spreads, nonadopters face a growing relative disadvantage, making individual adoption pr...
Authors: San Martín-Erice I, García-Vivar C, Furtado-Eraso S, Tamayo-Rodríguez I, San Martín-Rodríguez L, Soto-Ruiz N, Escalada-Hernández P
Anales del sistema sanitario de Navarra
The COVID-19 pandemic posed an unprecedented challenge to healthcare systems worldwide. Older adults living in nursing homes were particularly affected by the imposed isolation, experiencing considera...