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Multi-Scale Factor Analysis of High-Dimensional Brain Signals

Authors: Chee-Ming Ting, Hernando Ombao, Sh-Hussain Salleh

arXiv

In this paper, we develop an approach to modeling high-dimensional networks with a large number of nodes arranged in a hierarchical and modular structure. We propose a novel multi-scale factor analysi...

mental health psychology open access

MERLiN: Mixture Effect Recovery in Linear Networks

Authors: Sebastian Weichwald, Moritz Grosse-Wentrup, Arthur Gretton

arXiv

Causal inference concerns the identification of cause-effect relationships between variables, e.g. establishing whether a stimulus affects activity in a certain brain region. The observed variables th...

mental health psychology open access

Valid population inference for information-based imaging: From the second-level $t$-test to prevalence inference

Authors: Carsten Allefeld, Kai Görgen, John-Dylan Haynes

arXiv

In multivariate pattern analysis of neuroimaging data, 'second-level' inference is often performed by entering classification accuracies into a $t$-test vs chance level across subjects. We argue that...

mental health psychology open access

Scalable Algorithms for Generating and Analyzing Structural Brain Networks with a Varying Number of Nodes

Authors: Yu Jin, Joseph F. JaJa, Rong Chen, Edward H. Herskovits

arXiv

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resol...

mental health psychology open access

Tensor-Based Fusion of EEG and FMRI to Understand Neurological Changes in Schizophrenia

Authors: Evrim Acar, Yuri Levin-Schwartz, Vince D. Calhoun, Tülay Adalı

arXiv

Neuroimaging modalities such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) provide information about neurological functions in complementary spatiotemporal resolutio...

mental health psychology open access

Extracting the Multiscale Causal Backbone of Brain Dynamics

Authors: Gabriele D'Acunto, Francesco Bonchi, Gianmarco De Francisci Morales, Giovanni Petri

arXiv

The bulk of the research effort on brain connectivity revolves around statistical associations among brain regions, which do not directly relate to the causal mechanisms governing brain dynamics. Here...

mental health psychology open access

Assessment of synchrony in multiple neural spike trains using loglinear point process models

Authors: Robert E. Kass, Ryan C. Kelly, Wei-Liem Loh

arXiv

Neural spike trains, which are sequences of very brief jumps in voltage across the cell membrane, were one of the motivating applications for the development of point process methodology. Early work r...

mental health psychology open access

A Rational Analysis of the Speech-to-Song Illusion

Authors: Raja Marjieh, Pol van Rijn, Ilia Sucholutsky, Harin Lee, Thomas L. Griffiths, Nori Jacoby

arXiv

The speech-to-song illusion is a robust psychological phenomenon whereby a spoken sentence sounds increasingly more musical as it is repeated. Despite decades of research, a complete formal account of...

mental health psychology open access

Efficient methods for sampling spike trains in networks of coupled neurons

Authors: Yuriy Mishchenko, Liam Paninski

arXiv

Monte Carlo approaches have recently been proposed to quantify connectivity in neuronal networks. The key problem is to sample from the conditional distribution of a single neuronal spike train, given...

mental health psychology open access

On the Relation between Encoding and Decoding of Neuronal Spikes

Authors: Shinsuke Koyama

arXiv

Neural coding is a field of study that concerns how sensory information is represented in the brain by networks of neurons. The link between external stimulus and neural response can be studied from t...

mental health psychology open access

Harnessing XGBoost for Robust Biomarker Selection of Obsessive-Compulsive Disorder (OCD) from Adolescent Brain Cognitive Development (ABCD) data

Authors: Xinyu Shen, Qimin Zhang, Huili Zheng, Weiwei Qi

arXiv

This study evaluates the performance of various supervised machine learning models in analyzing highly correlated neural signaling data from the Adolescent Brain Cognitive Development (ABCD) Study, wi...

mental health psychology open access

Blood-based metabolic signatures in Alzheimer's disease

Authors: Francisca A. de Leeuw, Carel F. W. Peeters, Maartje I. Kester, Amy C. Harms, Eduard A. Struys, Thomas Hankemeier, Herman W. T. van Vlijmen, Sven J. van der Lee, Cornelia M. van Duijn, Philip Scheltens, Ayşe Demirkan, Mark A. van de Wiel, Wiesje M. van der Flier, Charlotte E. Teunissen

arXiv

Introduction: Identification of blood-based metabolic changes might provide early and easy-to-obtain biomarkers. Methods: We included 127 AD patients and 121 controls with CSF-biomarker-confirmed di...

mental health psychology open access

Crude EEG parameter provides sleep medicine with well-defined continuous hypnograms

Authors: Christoph Bandt

arXiv

To evaluate EEG data, one can count local maxima and minima on a fine scale, in a sliding window analysis. This straightforward calculation, which simplifies and improves previous work on permutation...

mental health psychology open access

Fast Nonconvex Deconvolution of Calcium Imaging Data

Authors: Sean Jewell, Toby Dylan Hocking, Paul Fearnhead, Daniela Witten

arXiv

Calcium imaging data promises to transform the field of neuroscience by making it possible to record from large populations of neurons simultaneously. However, determining the exact moment in time at...

mental health psychology open access

Bayesian Network Modeling of Causal Influence within Cognitive Domains and Clinical Dementia Severity Ratings for Western and Indian Cohorts

Authors: Wupadrasta Santosh Kumar, Sayali Rajendra Bhutare, Neelam Sinha, Thomas Gregor Issac

arXiv

This study investigates the causal relationships between Clinical Dementia Ratings (CDR) and its six domain scores across two distinct aging datasets: the Alzheimer's Disease Neuroimaging Initiative (...

mental health psychology open access