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Acetylcholine enhances deviance detection in Hodgkin-Huxley neuronal networks.

Authors: Fang F, Huang ZG, Chao ZC

Cognitive neurodynamics

Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease characterised by death of motor neurons (MNs) and resultant muscle paralysis. There is currently no cure for ALS with most p...

schizophrenia mental health open access

Second-To-Fourth Digit Ratio (2D:4D) in Breast Cancer: A Systematic Review.

Authors: Avcı A, Kaplan Serin E

American journal of human biology : the official journal of the Human Biology Council

Because high-altitude (HA) environments have a reduced atmospheric oxygen partial pressure compared with low-altitude locations, continued exposure to HA conditions poses a unique physiological challe...

schizophrenia mental health open access

Association of serum uric acid with incident vascular calcification in patients with type 2 diabetes mellitus: a retrospective cohort study.

Authors: Li X, He T, Li G, Liang X, Wang B, Liu Y, Zhao W, Zhu Z, Liu X

Frontiers in endocrinology

• High rates of inadequate follow-up: 44% of our cohort lacked follow-up within six months. • Predictors identified: both modifiable (discharge planning practices) and demographic factors (county of r...

schizophrenia mental health open access

Unique fluoroalkyl substituents: is there life after CF(3)?

Authors: Kubyshkin V, Mykhailiuk PK

Chemical science

Vascular calcification (VC) is the abnormal deposition of calcium phosphate, primarily hydroxyapatite, within the vascular walls. It serves as a common pathophysiological mechanism underlying several...

schizophrenia mental health open access

Distinct brain susceptibility alteration pattern in Parkinson's disease with drooling: evidence from quantitative susceptibility mapping.

Authors: Wang X, Chen K, Zhang X, Ji Y, Cheng W, Shi G, Fang X, Zhang Y, Zhang L

Quantitative imaging in medicine and surgery

Parkinson’s disease (PD) is a common progressive neurodegenerative disorder, pathologically characterized by the progressive loss of dopaminergic neurons in the nigrostriatal pathway. Clinically, it m...

schizophrenia mental health open access

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms.

Authors: Wu M, Zeng X, Cai Y, Chen H, Li Q, Yang H

Journal of cell communication and signaling

Positive symptoms, negative symptoms, and chronic cognitive impairment are the hallmarks of schizophrenia, a severe and diverse neuropsychiatric illness with significant functional disability. The pos...

schizophrenia mental health open access

Blood-Based Versus Crystalloid Cardiopulmonary Bypass Priming in Left Ventricular Assist Device Surgery: Impact on End-Organ Function and Survival.

Authors: Bonni S, Zayat R, Ramnath NWM, Hatam N, Tewarie L, Moza A, Sales MC

Interdisciplinary cardiovascular and thoracic surgery

A 42-year-old man presented with sudden-onset chest and back pain. He denied dysphagia, dyspnea, or other respiratory symptoms. On physical examination, vital signs were stable, and no significant abn...

schizophrenia mental health open access

Zebrafish oligodendrocyte lineage cells use the postsynaptic protein Gephyrin to myelinate GABAergic axons and limit myelin sheath growth.

Authors: Carey NJ, Doll CA, Appel B

Nature communications

Equine grass sickness (EGS or equine dysautonomia) is a predominantly fatal multiple-system neuropathy affecting grazing horses. It occurs throughout the UK and Northern Europe with a mortality rate b...

schizophrenia mental health open access

An electrophysiological and proteomics roadmap for human induced glutamatergic neurons: fine-tuning of culture conditions for pathophysiological studies.

Authors: Servetti M, Parodi G, Caramia M, Nano E, Bartolucci M, Marte A, Mazzoni G, Giubbolini S, Diab F, Petretto A, Valente P, Martinoia S, Baldassari S, Fassio A, Benfenati F, Corradi A, Sterlini B

Cell death discovery

Cognitive impairment is characterized by deficits in learning, memory, attention, and executive function and is commonly observed in older adults []. It has been associated with several metabolic abno...

schizophrenia mental health open access

Machine learning models for predicting postpartum convulsions using clinical indicators from PMA Ethiopia data.

Authors: Mulugeta C, Emagneneh T, Yetwale A, Yimer NB, Ayele M, Negese K, Tadese S, Alamrew A

Scientific reports

Cancer is a leading cause of mortality worldwide, with increasing incidence and disease burden reported in both developed and developing regions (, ). Despite advances in surgical techniques, chemothe...

schizophrenia mental health open access

Streptococcus-derived CpsA-CpsC fusion protein induces apoptosis in cervical cancer cells through in silico and in vitro methods.

Authors: Marzhoseyni Z, Shayestehpour M, Shaghaghi Z, Alvandi M, Esmaeili D

Scientific reports

Detection canines are dogs purposely trained to identify numerous potential threats, including narcotics (), explosives (), pathogens (), and invasive species (, ). Deployment of successful detection...

schizophrenia mental health open access

Identification of Metabolic Biomarkers in Bone Marrow Aspirate for Diagnosis, Prognosis, and Therapeutic Monitoring in Pediatric Langerhans Cell Histiocytosis.

Authors: Liu X, Wang J, Wang Y, Lin H, Zheng Q, Cai M, Cao X, Jiang H, Mao X

Annals of laboratory medicine

Type 1 diabetes (T1D) and phenylketonuria (PKU) are two distinct metabolic disorders whose co-occurrence presents unique clinical challenges. PKU is a rare inherited metabolic disorder caused by a def...

schizophrenia mental health open access

Effectiveness and Safety of Herbal Decoctions for Functional Dyspepsia in Korean Medicine Clinics: A Multicenter Prospective Cohort Study Protocol.

Authors: Park C, Ha NY, Kim J

Healthcare (Basel, Switzerland)

Mass spectrometry (MS) and chromatography have become crucial pillars of biomedical studies. Their coupling, indeed, allows researchers to tackle problems that range from the structural elucidation of...

schizophrenia mental health open access

Profiling miRNAs Involved in Human Oligodendrocyte Precursor Cell Differentiation and Maturation.

Authors: Barzegar M, Dhukhwa A, Patel VN, Velasquez FC, Das S, Patil AH, Halushka MK, Chamling X

Cells

Atherosclerosis is a chronic inflammatory disease and remains the leading cause of cardiovascular mortality worldwide [, ]. Elevated levels of oxidized low‐density lipoprotein (oxLDL) in the circulati...

schizophrenia mental health open access

The Transcriptomic and Proteomic Molecular Signatures of Equine Multiple-System Neuropathy (Grass Sickness).

Authors: Summers KM, Karagianni AE, Fernandez PL, Beard PM, Pirie RS, Keen JA, Wishart TM, McGorum BC

Cells

Machine learning is reshaping bioinformatics and biomedicine by enabling the analysis of high-dimensional molecular, clinical, imaging, and network-based data. With the rapid accumulation of genomic,...

schizophrenia mental health open access