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Showing 15 of 20167 papers

Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.

Authors: Streit F, Awasthi S, Hall ASM, Braun A, Niarchou M, Marouli E, Babajide O, Frank J, Zillich L, Callies CM, Avetyan D, Zillich E, Naamanka J, Gonzalez J, Harder A, Lu Y, Aherrahrou Z, Ahmad ZU, Ask H, Batzler A, Benros ME, Brand-de Wilde OM, Brunak S, Bruun MT, Christoffersen LAN, Colodro-Conde L, Coombes BJ, Corfield EC, Dahmen N, Didriksen M, Dinh KM, Djurovic S, Dowsett J, Drange OK, Dukal H, Edelmann S, Erikstrup C, Espinola MK, Fassbinder E, Faucon A, Ferreira de Sá DS, Foo JC, Gilles M, Gutiérrez-Zotes A, Hansen TF, Haraldsson M, Harper RP, Havdahl A, Heilbronner U, Herms S, Hjalgrim H, Hübel C, Jacob GA, Aagaard B, Jorgensen A, Jungkunz M, Kleindienst N, Knoblich N, Koglin S, Kraft J, Krebs K, Lee CW, Lin Y, Lis S, Lisoway A, Malogiannis IA, Martinsen A, Maslahati T, Merz K, Meyer-Lindenberg A, Mikkelsen S, Mikkelsen C, Mobascher A, Muntané G, Oddsson A, Ostrowski SR, Palviainen T, Pedersen OBV, Pedersen G, Quinn L, Reinhard MA, Ruths FA, Schott BH, Schredl M, Schwarz E, Schwarze CE, Schwinn M, Send TS, Sigurdsson E, Simon-Keller K, Skuladottir AT, Soler J, Sonley A, Sørensen E, Stefansson H, Straub P, Suvisaari J, Tesli M, Træholt J, Ullum H, Völker MP, Walters GB, Wang R, Witt CC, Zarbock G, Zill P, Zwart JA, DBDS Genomic Consortium, GLAD Study, HUNT All-In Psychiatry, Andreassen OA, Arntz A, Biernacka JM, Bohus M, Breen G, Chapman AL, Cichon S, Davis LK, Deuschle M, Euler S, Herpertz SC, Hummelen B, Jobst A, Kaprio J, Kennedy JL, Lehto K, Lieb K, Martorell L, McMain S, Musil R, Nieratschker V, Nöthen MM, Padberg F, Palotie A, Pascual JC, Perroud N, Ramos-Quiroga JA, Reichborn-Kjennerud T, Ribases M, Roepke S, Rujescu D, Sanchez-Roige S, Schilling C, Schmahl C, Stefansson K, Thorgeirsson TE, Turecki G, Vilella E, Werge T, Winsvold BS, Wrege J, Rietschel M, Ripke S, Witt SH

Nature genetics

Declines in physical and cognitive functions are major challenges for aging populations. Although multidomain interventions can help, maintaining long-term adherence remains difficult for many older a...

mental health psychology open access

AQP4-dependent enhancement of glymphatic function attenuates tau pathology and neurodegeneration in PS19 mice.

Authors: Yamada K, Ishida K, Sakamoto A, Shimada H, Watanabe M, Shimojo M, Igarashi H, Iwatsubo T

Molecular neurodegeneration

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that significantly affects the aging population. As the leading cause of dementia, AD accounts for 60–80% of all dementia cases wor...

mental health psychology open access

Acupuncture vs. Massage for Insomnia and Pain in Advanced Cancer: Exploratory RCT.

Authors: Kwag E, Fok RWY, Li QS, Baser RE, Garland SN, Liou KT, Mao JJ, McConnell K

Journal of pain and symptom management

Survival in complex environments requires efficient navigational strategies. From desert ants to humans, successful wayfinding, defined as navigating toward goals that are not directly visible, depend...

mental health psychology open access

Leveraging Advanced AI Frameworks for Dual PPAR α/γ Agonist Discovery in Alzheimer's Disease.

Authors: Chaturvedi N, Mishra V, Haque S, Khatoon S, Rawal K, Kumar V

ACS chemical neuroscience

In the United States, e-cigarettes are the most commonly used nicotine and tobacco product among young adults. Using e-cigarettes not only increases one’s exposure to harmful toxicants but may also in...

mental health psychology open access

Implementing after action review in an Irish tertiary hospital: a mixed-methods evaluation of safety culture and second victim experience and support.

Authors: McCarthy SE, Finn M, Valentelyte G, Boland F, Hogan C, Jenkins L, Keane T, Mellon L, Schwanberg L, Walsh A, Williams DJ, Rafter N

BMC health services research

One of the concerns of dentists is the anxiety control of patients during the local anesthetic injection. Over 25% of adults have been reported to be afraid of injections []. Syringe and needle phobia...

mental health psychology open access

Biphasic synaptic plasticity of the medial thalamic-cingulate pathway contributes to pain hypersensitivity in vivo.

Authors: Lin S, Hao S, Wu Y, Liu W, Wang J, Li L, Liu W, Zhuo M, Tao W

Molecular pain

The theory-driven, community-based participatory research-based systematic adaptation using the Stirman framework ensured transparent and reproducible documentation of all modifications. A comprehensi...

mental health psychology open access

Serotonergic System Dysregulation in Alzheimer's Disease.

Authors: Al-Ghraiybah NF, Alkhalifa AE, Spivey D, Averill T, Engelkemier B, Haro Lopez P, Stuckey MG, Jenkins L, Kaddoumi A

ACS chemical neuroscience

Stroke is increasingly conceptualized not merely as a focal lesion but as a disorder of distributed brain networks, characterized by large-scale disruptions in interhemispheric balance, functional con...

mental health psychology open access

Comparing the effect of photobiostimulation, pressure and topical anesthetic gel on reducing pain during maxillary infiltration injection: a clinical trial study.

Authors: Vatanpour M, Habibi Z, Tour Savadkouhi S, Radafshar M

BMC oral health

In Australia, per capita alcohol consumption has increased since 2019 [], and alcohol use continues to be a significant concern for public health [, ], as drinking is linked to over 200 health conditi...

mental health psychology open access

Comment on 'Real-World Evidence of the Effectiveness and Safety of Biosynthetic Semaglutide in Type 2 Diabetes: A Multicentre Study From Pakistan'.

Authors: Shahid F, Khan MF

Diabetes, obesity & metabolism

Autoimmune thyroid diseases are a group of chronic conditions affecting the thyroid gland, of which the most common is autoimmune hypothyroidism; that is, hypothyroidism resulting from Hashimoto’s thy...

mental health psychology open access

A novel gross deletion in the progranulin gene in four subjects with frontotemporal dementia.

Authors: Ricci M, Di Fede G, Caroppo P, Aprea V, Villa C, Romeo A, Tiraboschi P, Marti A, Grisoli M, Piccione MM, Cimini S, Rossi G

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Large language models (LLMs) have rapidly permeated higher education, offering new possibilities for academic writing, exam preparation, and personalised learning []. In dental education, where eviden...

mental health psychology open access

Associations between dietary vitamin K1 and K2 intake and incident dementia: findings from the Danish Diet, Cancer, and Health cohort.

Authors: Ghasemifard N, Sim M, Pokharel P, Li C, Linneberg A, Bjerregaard AA, Olsen A, Dahm CC, Radavelli-Bagatini S, Laws SM, Lewis JR, Hodgson JM, Bondonno NP

European journal of nutrition

Major depressive disorder (MDD), generalized anxiety disorder, bipolar disorder (BD), and posttraumatic stress disorder (PTSD) collectively constitute one of the most urgent global health crises of th...

mental health psychology open access

DTI-ALPS is not independently associated with overall survival beyond established prognostic factors in glioblastoma.

Authors: Schmidt L, Santaniello SD, Krenzlin H, Kronfeld A, Kollmann B, Tüscher O, Frauenknecht K, Jägersberg M, Altmann S, Brockmann MA, Othman AE

Journal of neuro-oncology

The study used purposive sampling with maximum variation across 12 primary hospitals. Methodological rigour and data saturation were ensured. The study included healthcare providers from multiple prof...

mental health psychology open access

Accuracy of operative time prediction in endometriosis surgery: results of a prospective randomized multicenter pilot study.

Authors: Duvnjak M, Mueller A, Binder S, Guttenberg P, Hornaus MT, Helfenritter J, Boosz A, Baev E

Archives of gynecology and obstetrics

Despite the wide availability of instruments for assessing child development, their internal structure is often not subjected to robust psychometric analyses. The (FOIDI), used in Brazil’s , had not...

mental health psychology open access

Impact of clinical pharmacist-led interventions on denosumab adherence.

Authors: Zuschnitt A, Lightheart E, Myers J, Khan AN

Archives of osteoporosis

The first of four sections describes the importance of SDM in general patient care, recognizing that dental patients are a part of this broader population. A brief historical context is also provided...

mental health psychology open access

Beyond MVPA minutes: physical activity phenotypes are associated with metabolic profiles in children with obesity.

Authors: Gatti A, Vandoni M, Cavallo C, Carnevale Pellino Carnevale Pellino V, Rossi V, Odone A, Zuccotti G, Calcaterra V

European journal of pediatrics

This study used a large, systematically sampled cohort of 404 participants from three public hospitals in a low-resource setting. The integration of the health belief model and health-related quality-...

mental health psychology open access