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Showing 15 of 20167 papers

Fusobacterium periodonticum promotes colorectal tumorigenesis via decanoic acid-driven neutrophil chemotaxis.

Authors: Jia X, Jiang L, Gong Y, Chu X, Yu W, Du J, Zhang J, Shang X, Wang P, Wang J, Li Y, Wang Z, Zhou R, Li Z, Zhu Y, Wu B, Li J, Yang Q

Nature communications

Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition characterized by re-experiencing, avoidance, negative emotions and thoughts, and hyperarousal following exposure to severe...

mental health psychology open access

FRAME: Fine-Resolution Asymmetric Migration Estimation.

Authors: Shen H, Novembre J

Nature communications

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a cascade of pathological processes, from the accumulation of misfolded proteins such as β-amyloid (Aβ) and hyperphosphorylate...

mental health psychology open access

Migratory jackpot individuals fuel rapid ecotype shifts in Galaxias fishes.

Authors: Iwikau A, Augspurger J, Bailie MA, McCulloch GA, Darestani MM, King TM, Closs GP, Ingram T, Lokman PM, Deagle B, Burridge CP, Dutoit L, Waters JM

Nature communications

The advent of single-cell RNA sequencing has significantly revolutionized our understanding of cellular diversity in the brain. Large-scale transcriptomic atlases provide invaluable resources for diss...

mental health psychology open access

Neuron type-specific translatomes in dorsal hippocampus during early memory consolidation.

Authors: Oliveira MM, Mosto O, Carney R, Liu WJ, Mamcarz M, Makinde E, Lu EH, Ruiz KSA, Schultz CC, Leckie C, Carew TJ, Klann E

Nature communications

Rethinking machine cognition - beyond data-driven learning: Human cognition excels at new tasks with minimal prior experience through reasoning, by dedicating cognitive resources, such as extended thi...

mental health psychology open access

Reasoning in machine vision by learning fast and slow thinking.

Authors: Saeed SU, Wang Y, Kasivisvanathan V, Davidson BR, Clarkson MJ, Hu Y, Alexander DC

Nature communications

In spatially structured populations, migration over generations shapes genetic variation and often leads to isolation-by-distance—a phenomenon in which geographically proximal individuals are more gen...

mental health psychology open access

Agreement between relatives of Parkinson's patients and clinical observer in home diary assessments.

Authors: Janz C, Timpka J, Storch A, Paul G, Odin P

Journal of Parkinson's disease

Generalization is at the heart of visually guided behavior. We perform visual generalization every time we ignore the vast amount of irrelevant information bombarding our visual system to identify an...

mental health psychology open access

Cognitive trajectories before and after geriatric hip fracture: a matched longitudinal analysis of the Health and Retirement Study, 1996-2016.

Authors: Hu H, Deng F, Chen Z, Chen B

BMC geriatrics

In the post-pandemic era, depressive disorders have become increasingly prevalent. Although their incidence varies among countries, approximately 20% of individuals are estimated to experience depress...

mental health psychology open access

Analysis of whole genome sequencing and plasma metabolomics unveil genetic determinants and clinical implications for human health.

Authors: Wang YX, Qiang YX, Ge YJ, Deng YT, Wu BS, Yang L, Chen YL, He XY, He Y, Yao BR, Fei CJ, Yin RY, You J, Feng JF, Cheng W, Yu JT

Nature communications

The birth of a new memory involves the synchronous engagement of a heterogeneous population of neurons, promoting molecular changes that strengthen the connectivity of a neuronal ensemble in the brain...

mental health psychology open access

Generating synthetic multi-national longitudinal cohorts for clinically grounded HIV research.

Authors: Liang ZJ, Li Z, Jackson NJ, Guo KH, Caro-Vega Y, Moreira RI, Paredes F, Bernadin J, Varela D, Cesar C, Blasimme A, Perkins JM, Asiaee A, Duda SN, Malin BA, Shepherd BE, Yan C

Nature communications

Intergroup conflict is a potent evolutionary force that has shaped social structure, territoriality and cooperation from ants to apes, including in humans. Contests between conspecific groups have bee...

mental health psychology open access

Right amygdala ablation reduces maladaptive negative interpretation bias and symptoms in a patient with post-traumatic stress disorder.

Authors: Xie T, van Rooij SJH, Sun S, Bryson NK, Demarest P, Park H, Maccotta L, Wang S, Brunner P, Willie JT

Nature communications

Menopause typically occurs at an average age of 51 and is characterized by a gradual decline in ovarian reproductive hormone production []. Menopause increases the risk for chronic non-communicable di...

mental health psychology open access

Cluster replicability in single-cell and single-nucleus atlases of the mouse brain.

Authors: French L, Suresh H, Gillis J

Nature communications

Processed meats are meat products treated by techniques such as smoking, salting, and curing to improve product quality and storage stability. Consumption of processed meat products is gradually incre...

mental health psychology open access

Early post-hospital trajectories of health-related quality of life for younger adult patients with traumatic brain injury.

Authors: Oyesanya TO, You H, Loflin C, Smith PJ, Bettger JP

Archives of physical medicine and rehabilitation

Parkinson's disease (PD) is the most common movement disorder, and after five years with the disease more than 50% of patients develop motor fluctuations. These fluctuations have been shown to negativ...

mental health psychology open access

Healthcare interventions to improve health outcomes for racially/ethnic minoritised people with multiple long-term conditions: a systematic review and narrative synthesis.

Authors: Hayanga B, Joshi M, Hartley K, Oyibo P, Sarwar R, Tariq S, Kashyap M, BƩcares L

BMC public health

Longitudinal clinical cohort data are invaluable for tracking the evolving needs and outcomes of individuals with chronic conditions. For people living with HIV (PWH), long-term clinical cohorts have...

mental health psychology open access

Associations of plasma biomarkers of Alzheimer's disease pathology with modifiable risk factors and cognitive and functional outcomes: evidence from cross-sectional prediction and latent path analyses

Authors: Kirk M, Kwon J, Mavromati K, Gordon-Boyle A, Bhui K, Koychev I, Bauermeister S, Tsiachristas A

Alzheimer's research & therapy

Biological ageing clocks integrate multiple biomarkers—such as epigenetic and proteomic measures—to capture biologically meaningful variation in ageing that goes beyond chronological age and helps pre...

mental health psychology open access

Development and validation of a healthy lifestyle and behavioral score for predicting metabolic syndrome: evidence from a 24-year longitudinal health check-up cohort in Taiwan.

Authors: Cambia JM, Chan TC

The international journal of behavioral nutrition and physical activity

Pressure injuries (PIs) are increasingly prevalent secondary complications of spinal cord injury or disorder (SCI/D), profoundly affecting individuals’ quality of life with significant cost to the hea...

mental health psychology open access