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Showing 15 of 20167 papers

Evaluating a motivational interviewing-based communication program for nurses in advance care planning: a quasi-experimental study.

Authors: Kim MY, Kim J

BMC palliative care

Suicide is the second leading cause of death in the United States for individuals between the ages of 10 and 34 and the fourth leading contributor of years of potential life lost before 65 []. In addi...

mental health psychology open access

Increasing dose of esketamine for supplemental analgesia after complex spinal fusion surgery: a randomized and double-blind trial.

Authors: Guo ZM, Cui F, Zhang Y, Ma JH, Wang DX

BMC anesthesiology

Advance care planning (ACP) enables individuals at any stage of health or illness to discuss and document their future medical care preferences [, ]. Through ongoing dialogue between patients, familie...

mental health psychology open access

The GALENOS approach to triangulating evidence: a structured approach for integrating information from human and animal studies.

Authors: Tonia T, Higgins JPT, Chiocchia V, Downs J, Wheeler E, Potts J, Smith KA, Macleod M, Malhi GS, Cipriani A, Salanti G

BMC medical research methodology

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterised by persistent deficits in social communication and interaction, and restricted, repetitive patterns of behaviour, interes...

mental health psychology open access

Phosphoproteomic profiling reveals post-translational dysregulation in Huntington's disease patient-derived neurons.

Authors: Danics L, Muralidharan C, Varga Á, Rezeli M, Gil J, Abbas AA, Pap Á, Park AS, Cserhalmi M, Legault EM, Sőth Á, Jamniczky D, Zsoldos R, Barker RA, Róna G, Drouin-Ouellet J, Markó-Varga G, Darula Z, Pircs K

Cellular & molecular biology letters

Depression is one of the most prevalent and disabling mental disorders worldwide and is a major contributor to global disease burden and mortality []. Recent estimates suggest that approximately 350 m...

mental health psychology open access

Dup15q model mice exhibit impaired gastrointestinal motility and a constipation-like phenotype, alleviated by prucalopride.

Authors: Balasuriya GK, Tamada K, Nomura J, Cirillo C, Takumi T

Translational psychiatry

Congenital heart disease (CHD) is among the most common congenital anomalies worldwide and remains an important contributor to infant morbidity and mortality [, ]. Global estimates suggest that CHD af...

mental health psychology open access

Myo-inositol concentration in the medial prefrontal cortex is associated with changes in brain white matter microstructure in early psychosis.

Authors: Pavan T, Wang Q, AlemĂĄn-GĂłmez Y, Jenni R, Cleusix M, Alameda L, Q Do K, Conus P, Hagmann P, Steullet P, Klauser P, Xin L, Jelescu I

Translational psychiatry

Amyotrophic lateral sclerosis (ALS) is a disease characterized by muscle atrophy due to the degeneration of neurons in the cortex, brainstem and spinal cord (; ; ). The disease starts with mild sympto...

mental health psychology open access

Constipation is associated with an increased risk of depression: A systematic review and meta-analysis of observational studies.

Authors: Ren ZY, Guo ZY, Diao Q, Hashimoto K, Yang JJ, Zhang GF

Translational psychiatry

Obesity is a global epidemic [] with significant personal, economic, and societal impacts [, ]. Given its association with numerous comorbidities and an increased risk of all-cause mortality [–], the...

mental health psychology open access

An integrative mendelian randomisation and drug mechanism framework for target prioritisation and therapeutic repurposing in major depression.

Authors: Ter Kuile AR, Finan C, Chopade S, van Vugt M, Hukerikar N, Barral S, Stringaris A, Schmidt AF, Kuchenbaecker K, Pingault JB

Translational psychiatry

As technological advancements continue to make significant changes in the healthcare landscape, the integration of innovative technologies in the healthcare training system has become increasingly ess...

mental health psychology open access

Sex-specific associations of depression with inflammatory markers: a systematic review and meta-analysis.

Authors: Szabo YZ, Nishimi K, Smirnova M, Niles A, Lerche AS, Tsai HA, Afroz S, Huey N, Mathur M, O'Donovan A

Translational psychiatry

Delivering bad news, particularly in end-of-life care, is one of the most emotionally and ethically demanding responsibilities in nursing. The task becomes even more complex when the recipients are pa...

mental health psychology open access

Aging in Behçet's syndrome: an overlooked risk for late-life cognitive impairment.

Authors: Spinetti D, Massara M, Marrone C, Salvador E, Pepe E, Ravelli A, Padoan R, Ramonda R, Ceolin C, Sergi G, Mapelli D, De Rui M, Devita M

Aging clinical and experimental research

Behçet’s syndrome (BS) or Behçet’s disease (BD) is a chronic multisystem inflammatory disorder characterized by a relapsing-remitting course and several clinical manifestations, including oral and gen...

mental health psychology open access

Resistance pathways and next-generation treatments in chronic lymphocytic leukemia.

Authors: Bellemrrabet R, Rachid E, Lahmouad M, Aboussaleh Y, Al Abdulmonem W, Bouyahya A, Abboussi O, Amahdar L

Discover oncology

Tic disorders (TD) are common neurodevelopmental conditions characterized by sudden, rapid, recurrent, non-rhythmic movements or vocalizations with onset in childhood. The Diagnostic and Statistical M...

mental health psychology open access

Ultrasound-induced blood-brain barrier opening in Alzheimer's disease: a systematic review of clinical studies.

Authors: Niknam N, Songhori N, Nekahi N, Kavian M, Khosravi F, Fard AM, Moshiri Y, Haghshenas N, Sadegh MH, Torabi P

Aging clinical and experimental research

As the country with the largest elderly population in the world, China is projected to have 400 million residents aged 65 years and older by 2050, thereby facing substantial challenges associated with...

mental health psychology open access

Disparate privacy risks from medical AI.

Authors: Knolle MA, Menten MJ, Jungmann F, Meissen F, Glocker B, Rueckert D, Kaissis G

Nature

In amatched HRS cohort of US adults aged 65 years or older, cognitive disadvantage was evident before the fracture-report index. Global cognition was lower at the index interview and showed additional...

mental health psychology open access

HCCD-DS v2: a transparent synthetic benchmark for human-AI decision support under contextual uncertainty.

Authors: Kesgin K

Scientific reports

Decision Support Systems (DSS) are increasingly implemented as hybrid pipelines in which machine learning models generate recommendations and humans decide whether to follow or override them. In this...

mental health psychology open access

Stable readout of visual representations mediates flexible generalization.

Authors: Srinath R, Czarnik MM, Cohen MR

Nature communications

Dementia is one of the world’s most pressing health challenges. Disease cases are projected to surge from 55 million in 2019 to over 153 million by 2050 []. This places an unprecedented burden on alre...

mental health psychology open access