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Showing 15 of 20167 papers

Chrono-Nanomedicine at the Barrier: Circadian Rhythms Influence the Delivery of Donepezil Across the BCSFB.

Authors: Cardoso MR, Duarte AC, Mineiro R, Ferreira M, Sousa Â, Gallardo E, Ishikawa H, Schwerk C, Schroten H, Santos C, Costa D, Quintela T

International journal of molecular sciences

In chronic metabolic diseases such as obesity, dyslipidemia, and type 2 diabetes mellitus (T2DM), subacute chronic inflammation occurs, characterized by cytokine release. These cytokines induce insuli...

cognitive behavioral therapy mental health open access

Bioactive Compounds from Medicinal and Edible Plants for Anti-Aging: A Systematic Review of Molecular Mechanisms, Delivery Systems, and Clinical Evidence.

Authors: Ma Z, Huang B, Chen K, Yuan R, Li L, Shen Y

Foods (Basel, Switzerland)

Spinal cord injury (SCI) is a serious neurological condition that can cause permanent motor, sensory, and autonomic impairment []. SCI is most commonly traumatic, resulting from mechanisms such as spo...

cognitive behavioral therapy mental health open access

Predictors of 30-Day Healthcare Utilization After Telemedicine Management of Minimal Traumatic Intracranial Hemorrhage.

Authors: Riggenbach ZW, Teng JM, Kelly A, Williams B, Lutgens J, Akinmoladun O, Inouye P

Cureus

The resting motor threshold (RMT) is a fundamental measurement in transcranial magnetic stimulation (TMS) studies and is defined as the lowest stimulus intensity capable of evoking MEPs with a peak-to...

cognitive behavioral therapy mental health open access

Acute hyperactive delirium-like episode during dexmedetomidine sedation after recent discontinuation of long-term reserpine therapy: a case report.

Authors: Zhang B, Han Y, Zong L, Zhang L

Frontiers in medicine

Sacral neuromodulation (SNM) has emerged as an effective minimally invasive therapy for refractory lower urinary tract dysfunction (LUTD) via electrical stimulation of the S2–S4 sacral nerve roots []....

cognitive behavioral therapy mental health open access

Inflammation in atherosclerosis: Drivers, mechanisms and therapies.

Authors: Su Z, Xu S

Acta pharmaceutica Sinica. B

A systematic literature review was performed by searching Web of Science and PubMed using the following terms: (“ZBTB20”) AND (“Kallmann syndrome” OR “congenital hypogonadotropic hypogonadism” OR “GnR...

cognitive behavioral therapy mental health open access

Neutrophil-hitchhiking nanoplatform overcomes blood-brain barrier to treat cerebral ischemia-reperfusion injury via ferroptosis inhibition and microglial modulation.

Authors: Li S, Yang B, Fan K, Mu Q, Shen H, Zhang T, Xu X, Bai H, Tang L, Yan S, Lan Q

Frontiers in pharmacology

cognitive behavioral therapy mental health open access

Phenotype-guided selection of venlafaxine and topiramate for vestibular migraine: a narrative review.

Authors: Wang T, Luo S, Han J, Li H, Wang Y, Zhang X, Li D, Yu X

Frontiers in neuroscience

Traumatic injury has long been conceptualized as an acute, time-limited event; however, modern trauma epidemiology increasingly supports its characterization as a chronic, relapsing condition marked b...

cognitive behavioral therapy mental health open access

Impact of sensory integration in modulating neuronal oscillation bands and antagonist vibratory response during co-vibration.

Authors: Thu KW, Tanamachi K, Okawada M, Kuwahara W, Kaneko F

Frontiers in human neuroscience

In the United Stated the annual rate of stroke is approximately 795,000 people (). Of those ~ 610000 are first stroke events and 185,000 are recurrent strokes (). The direct and indirect costs of stro...

cognitive behavioral therapy mental health open access

From Uptake to Therapeutic Function in Engineered Exosome Delivery Systems.

Authors: Li Y, Jin L, Gao P, Li M, Zhao Z, Jiang J, An M, Li F

Research (Washington, D.C.)

Evidence-based medicine (EBM) has profoundly reshaped clinical and public health practice by privileging methodological rigor, reproducibility, and hierarchical grading of evidence.[] Within this arch...

cognitive behavioral therapy mental health open access

Contemporary management of sarcoidosis.

Authors: Khine NW, Fletcher S

Frontiers in medicine

Chronic pain neuroscience has advanced significantly in recent years, identifying central nervous system (CNS) mechanisms that contribute to pain chronification. Chronic pain is prevalent, heterogeneo...

cognitive behavioral therapy mental health open access

Diagnosis and treatment of vitamin B12 deficiency in children.

Authors: Kanvinde P, Khurana R, Mudaliar S

Frontiers in nutrition

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and autism spectrum disorder (ASD), affecting approximately 1 in 4,000 males and 1 in 4,000–8,000 females (). FXS...

cognitive behavioral therapy mental health open access

Affective tactile stimulation ameliorates chronic pain and comorbid anxiety by modulating hippocampal CA1 oscillations and functional connectivity.

Authors: Zeng L, Jin Y, Chen L, Lai Y, Zhu Y, Zhang Y, Feng X, Li J, Li W

Frontiers in molecular neuroscience

Chronic inflammation contributes not only to autoimmune diseases such as rheumatoid arthritis (RA), but also to the onset and progression of a wide range of disorders, including neurodegenerative, neu...

cognitive behavioral therapy mental health open access

Editorial: Digital medicine and artificial intelligence.

Authors: Wang MH, Lopes NP, OsĂłrio NS

Frontiers in artificial intelligence

VM is now an established diagnostic entity at the interface of headache medicine, neuro-otology, and functional vestibular disorders (; ). The 2022 BĂĄrĂĄny Society/International Headache Society update...

cognitive behavioral therapy mental health open access

Immersive virtual reality for pediatric burn pain and early rehabilitation.

Authors: Lu L, Li W, Ye S, Dai P

Frontiers in pediatrics

Burn injury is a leading cause of morbidity, hospitalization, and long-term disability in children (). Even limited injuries often necessitate repeated medical visits, wound care, and rehabilitation,...

cognitive behavioral therapy mental health open access

Knowledge, attitudes, and perspectives on gene therapy for Fragile X syndrome: results from two community and caregiver surveys.

Authors: Chen V, Vomvos M, De Sonia A, Rosselot H, Lozano R

Frontiers in molecular neuroscience

Dementia represents a rapidly escalating global public health priority, with advancing age constituting the strongest non-modifiable risk factor. In 2021, the number of individuals living with dementi...

cognitive behavioral therapy mental health open access