Authors: Milani GP, Riccò M, Agosti M, Agostiniani R, Amigoni A, Aromatario C, Barbi E, Benini F, Cersosimo A, De Zen L, Dibello D, Chiappini E, Divisic A, Frati P, Galante D, Ingelmo PM, Kotzeva S, Luxardo N, Manfredini L, Minardi C, Moresco L, Moretti AM, Moscaritolo L, Crotti Partel M, Pellegatta F, Pitino S, Rebesco B, Salè EO, Levet PS, Signorini R, Simonini A, Somaini M, Suppiej A, Sotgiu S, Tornesello A, Verdoni F, Vittori A, Zangardi T, Pilloni S, Sassetti C, Septelici D, Brigadoi G, Donà D, Lago P, Squazzini G, Esposito S, Italian Study Group on Pediatric Pain Management
Journal of clinical medicine
Electronic devices implanted in the body provide powerful tools for diagnosis, therapeutics and research. For example, bioelectronic implants for brain stimulation have provided biological insights an...
Authors: Wu Y, Li L, Tian J, Liu L, Du K, Shao Z, Cheng T, Cao X, Wang T
International journal of molecular sciences
RNA polymerase II transcribes the vast majority of the mammalian genome, yet most of this output, including promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), antisense transcripts, and r...
Authors: Chen Z, Tian F, Wan X, Zhou F, Wu F
Journal of clinical medicine
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by impairments in social communication, repetitive and stereotyped behaviors, restricted interests, and sen...
Authors: Khan M, Choi H, Ahmad S, Lee S, Park JC, Han I
International journal of molecular sciences
Diabetes Mellitus (DM), a prevalent global public health concern, manifests as a non-communicable metabolic disorder characterized by hyperglycemia and various complications. Global estimates in 2019...
Authors: Sgarioni AC, Farina GS, Bressan TS, Dalfovo MP, De Carli GM, Giovanardi HJP, Giovanardi GS, Selistre LDS, Rahmi Garcia RM
Journal of clinical medicine
Extraventricular neurocytoma (EVN) is an uncommon neuronal neoplasm classified by the World Health Organization (WHO) within the group of neuronal and glioneuronal tumors and is currently recognized a...
Authors: Newman AG, Singh PB
Cells
Colony-stimulating factor 1 receptor–related disorder (CSF1R-RD) is a rare hereditary neurodegenerative condition caused by pathogenic variants in the gene [,]. CSF1R-RD is typically a rapidly progre...
Authors: Tortoriello S, Rossi S, Della Valle I, D'Ambrosi N, Cozzolino M
Cells
Cells maintain accurate translation to ensure proper protein synthesis. Canonical translation initiates when the small (40S) ribosomal subunit scans the mRNA to recognize the AUG start codon, followed...
Authors: Akhmetzyanova E, Nasybullina E, Rizvanov A, Mukhamedshina Y
International journal of molecular sciences
Dietary and lifestyle factors are recognized as major determinants of cancer risk. Indeed, the development of several malignancies, including colorectal cancer (CRC), breast cancer, ovarian cancer, an...
Authors: Hyung SW, Park UJ, Ryu JH, Chung S
Journal of clinical medicine
Epilepsy is one of the most prevalent neurological disorders, affecting approximately 50 million people worldwide [,]. Conceptually, an epileptic seizure is defined as a transient occurrence of signs...
Authors: Trofimov A, Shcherbakova K, Schwarz A, Akbay B, Karapina O, Myrkhiyeva Z, Shirokov E, Kizatov B, Zhukanov K, Baktursyn A, Isseyeva M, Namiyaliyeva A, Sarapultsev A, Komelkova M, Lookin O, Tokay T
International journal of molecular sciences
By the end of 2021, China’s population aged 65 and older reached 191 million, representing 13.5% of the total population and accounting for one in four older adults globally. This rapid demographic sh...
Authors: Wang Y, Cao Z, Zhang C, Ying Y, Zhu G, Wang J, Hou X, Zhang D, Zheng Z, Shao H, Liu F, Ma X
International journal of molecular sciences
Pathogenic variants in genes involved in inhibitory neurotransmission comprise a substantial fraction of known monogenetic causes of neurologic disorders, including epilepsies and more severe developm...
Authors: Riga V, Aniol V, Gulyaeva N
International journal of molecular sciences
Cells require constant transcription and translation to maintain function. Given their unique role in brain connectivity, neurons need carefully regulated protein synthesis to perform optimally. Neuro...
Authors: López-Prado E, Casal-Guisande M, Mosteiro-Añón M, Cerqueiro-Pequeño J, Fernández-Villar A, Torres-Durán M
Journal of clinical medicine
As a critical cardiopulmonary replacement technology, extracorporeal membrane oxygenation (ECMO) can partially or completely replace cardiopulmonary function to maintain systemic oxygenation, and has...
Authors: Günner ME, Eraslan Ö
Healthcare (Basel, Switzerland)
Irritable bowel syndrome (IBS) represents a common type of functional gastrointestinal disorder (FGID). Globally, approximately 20% of the general population is impacted by IBS, which substantially in...
Authors: Ayyadurai VAS, Manoharan Y, Deonikar P
Cells
Obesity is a major and rapidly growing global health problem associated with multiple cardiometabolic and systemic comorbidities, including type 2 diabetes mellitus (T2DM), dyslipidemia, cardiovascula...