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Reduced Efficiency in the Attentional Network During Distractor Suppression in Mild Cognitive Impairment

Authors: Jatupong Oboun, Piyanon Charoenpoonpanich, Anna Raksapatcharawong, Chaipat Chunharas, Itthi Chatnuntawech, Chainarong Amornbunchornvej, Sirawaj Itthipuripat

arXiv

Mild Cognitive Impairment (MCI) is a critical transitional stage between normal cognitive aging and dementia, making its early detection essential. This study investigates the neural mechanisms of dis...

mental health psychology open access

How can methods for classifying and clustering trajectories be used for prevention trials? An example in Alzheimer's disease area

Authors: Céline Bougel, Sébastien Déjean, Caroline Giulioli, Philippe Saint-Pierre, Nicolas Savy, Sandrine Andrieu

arXiv

Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in...

mental health psychology open access

Inpainting the Neural Picture: Inferring Unrecorded Brain Area Dynamics from Multi-Animal Datasets

Authors: Ji Xia, Yizi Zhang, Shuqi Wang, Genevera I. Allen, Liam Paninski, Cole Lincoln Hurwitz, Kenneth D. Miller

arXiv

Characterizing interactions between brain areas is a fundamental goal of systems neuroscience. While such analyses are possible when areas are recorded simultaneously, it is rare to observe all combin...

mental health psychology open access

CITS: Nonparametric Statistical Causal Modeling for High-Resolution Neural Time Series

Authors: Rahul Biswas, SuryaNarayana Sripada, Somabha Mukherjee, Reza Abbasi-Asl

arXiv

Identifying causal interactions in complex dynamical systems is a fundamental challenge across the computational sciences. Existing functional connectivity methods capture correlations but not causati...

mental health psychology open access

Ontology-constrained multi-LLM scoring of hypothesis support in the predictive processing literature

Authors: Hamed Nejat, Alexander Maier, Jesse Spencer-Smith, André M. Bastos

arXiv

Fragmentation is common in interdisciplinary fields with diverse methods and theoretical commitments. Predictive coding neuroscience is a clear example: its literature spans computational theory, elec...

mental health psychology open access

Spatial Neighboring Scattering Transform: A Cross-Channel Amplitude Coupling Measure for EEG Connectivity

Authors: Md. Taksimul Ahsan Tawhid, Nasif Ahmed Rafe, Alif Tahmid Priyom, K. M. Mustafizur Rahman

arXiv

The functional organization of the brain relies on coordinated activity across spatially distributed regions, making the analysis of inter-regional dependencies fundamental. Existing connectivity meas...

mental health psychology open access

Mixed Effects Spectral Vector Autoregressive Model: With Application to Brain Connectivity

Authors: Anastasiia Malinovskaia

arXiv

The primary goal of this paper is to develop a method that quantifies how activity in one brain region can explain future activity in another region. Here, we propose the mixed effects spectral vector...

mental health psychology open access

PATHFINDER: Designing Stimuli for Neuromodulation through data-driven inverse estimation of non-linear functions

Authors: Chaitanya Goswami, Pulkit Grover

arXiv

There has been tremendous interest in designing stimuli (e.g. electrical currents) that produce desired neural responses, e.g., for inducing therapeutic effects for treatments. Traditionally, the desi...

mental health psychology open access

Human body-sway steady-state responses to small amplitude tilts and translations of the support surface -- Effects of superposition of the two stimuli

Authors: Vittorio Lippi, Christoph Maurer, Thomas Mergner

arXiv

Upright stance tested with a superposition of support surface tilt and translation. Steady state response is characterized by frequency response function. Interaction between two stimuli absent in mos...

mental health psychology open access

Continuous and Atlas-free Analysis of Brain Structural Connectivity

Authors: William Consagra, Martin Cole, Xing Qiu, Zhengwu Zhang

arXiv

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determin...

mental health psychology open access

Dynamic modeling of spike count data with Conway-Maxwell Poisson variability

Authors: Ganchao Wei, Ian H. Stevenson

arXiv

In many areas of the brain, neural spiking activity covaries with features of the external world, such as sensory stimuli or an animal's movement. Experimental findings suggest that the variability of...

mental health psychology open access

A Flexible Bayesian Clustering of Dynamic Subpopulations in Neural Spiking Activity

Authors: Ganchao Wei, Ian H. Stevenson, Xiaojing Wang

arXiv

With advances in neural recording techniques, neuroscientists are now able to record the spiking activity of many hundreds of neurons simultaneously, and new statistical methods are needed to understa...

mental health psychology open access

Fractal-based Correlation Analysis for Resting State Functional Connectivity of the Rat Brain in Functional MRI

Authors: Wonsang You, Joerg Stadler

arXiv

The most studies on functional connectivity have been done by analyzing the brain's hemodynamic response to a stimulation. On the other hand, the low-frequency spontaneous fluctuations in the blood ox...

mental health psychology open access

Linear Time GPs for Inferring Latent Trajectories from Neural Spike Trains

Authors: Matthew Dowling, Yuan Zhao, Il Memming Park

arXiv

Latent Gaussian process (GP) models are widely used in neuroscience to uncover hidden state evolutions from sequential observations, mainly in neural activity recordings. While latent GP models provid...

mental health psychology open access

Estimating the number of neurons in multi-neuronal spike trains

Authors: Mengxin Li, Wei-Liem Loh

arXiv

A common way of studying the relationship between neural activity and behavior is through the analysis of neuronal spike trains that are recorded using one or more electrodes implanted in the brain. E...

mental health psychology open access