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Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

Authors: Pengcheng Zhou, Shanna L. Resendez, Jose Rodriguez-Romaguera, Jessica C. Jimenez, Shay Q. Neufeld, Garret D. Stuber, Rene Hen, Mazen A. Kheirbek, Bernardo L. Sabatini, Robert E. Kass, Liam Paninski

arXiv

In vivo calcium imaging through microscopes has enabled deep brain imaging of previously inaccessible neuronal populations within the brains of freely moving subjects. However, microendoscopic data su...

mental health psychology open access

Neural stochastic codes, encoding and decoding

Authors: Hugo Gabriel Eyherabide

arXiv

Understanding brain function, constructing computational models and engineering neural prosthetics require assessing two problems, namely encoding and decoding, but their relation remains controversia...

mental health psychology open access

High-dimensional cluster analysis with the Masked EM Algorithm

Authors: Shabnam N. Kadir, Dan F. M. Goodman, Kenneth D. Harris

arXiv

Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conv...

mental health psychology open access

Statistical Network Analysis for Functional MRI: Summary Networks and Group Comparisons

Authors: Cedric E. Ginestet, Arnaud P. Fournel, Andrew Simmons

arXiv

Comparing weighted networks in neuroscience is hard, because the topological properties of a given network are necessarily dependent on the number of edges of that network. This problem arises in the...

mental health psychology open access

Spatio-temporal patterns in multi-electrode array local field potential recordings

Authors: Bronwyn Woods

arXiv

This paper presents a method for the detection of traveling waves of activity in neural recordings from multi-electrode arrays. The method converts local field potential measurements into the phase do...

mental health psychology open access

Optimal Transport for Latent Integration with An Application to Heterogeneous Neuronal Activity Data

Authors: Yubai Yuan, Babak Shahbaba, Norbert Fortin, Keiland Cooper, Qing Nie, Annie Qu

arXiv

Detecting dynamic patterns of task-specific responses shared across heterogeneous datasets is an essential and challenging problem in many scientific applications in medical science and neuroscience....

mental health psychology open access

Diversity in the radiation-induced transcriptomic temporal response of mouse brain tissue regions

Authors: Karolina Kulis, Sarah Baatout, Kevin Tabury, Joanna Polanska, Mohammed Abderrafi Benotmane

arXiv

A number of studies have indicated a potential association between prenatal exposure to radiation and late mental disabilities. This is believed to be due to long-term developmental changes and functi...

mental health psychology open access

Covariance Regression for High Dimensional Neural Data via Graph

Authors: Ganchao Wei

arXiv

Modern recording techniques enable neuroscientists to simultaneously study neural activity across large populations of neurons, with capturing predictor-dependent correlations being a fundamental chal...

mental health psychology open access

An Analysis of How Spatiotemporal Dynamic Models of Brain Activity Could Improve MEG/EEG Inverse Solutions

Authors: Camilo Lamus, Matti S. Hamalainen, Emery N. Brown, Patrick L. Purdon

arXiv

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural...

mental health psychology open access

Random Effects Models for Understanding Variability and Association between Brain Functional and Structural Connectivity

Authors: Lingyi Peng, Qiaochu Wang, Yaotian Wang, Jie He, Xu Zou, Shuoran Li, Dana L. Tudorascu, David J. Schaeffer, Lauren Schaeffer, Diego Szczupak, Emily S. Rothwell, Stacey J. Sukoff Rizzo, Gregory W. Carter, Afonso C. Silva, Tingting Zhang

arXiv

The human brain is organized as a complex network, where connections between regions are characterized by both functional connectivity (FC) and structural connectivity (SC). While previous studies hav...

mental health psychology open access

Bootstrap Prediction and Confidence Bands for Frequency Response Functions in Posturography

Authors: Vittorio Lippi

arXiv

The frequency response function (FRF) is an established way to describe the outcome of experiments in posture control literature. The FRF is an empirical transfer function between an input stimulus an...

mental health psychology open access

Bayesian Dynamical Modeling of Fixational Eye Movements

Authors: Lisa Schwetlick, Sebastian Reich, Ralf Engbert

arXiv

Humans constantly move their eyes, even during visual fixations, where miniature (or fixational) eye movements occur involuntarily. Fixational eye movements comprise slow components (physiological dri...

mental health psychology open access

Decomposed Linear Dynamical Systems (dLDS) for learning the latent components of neural dynamics

Authors: Noga Mudrik, Yenho Chen, Eva Yezerets, Christopher J. Rozell, Adam S. Charles

arXiv

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neur...

mental health psychology open access

Optimal Visual Search with Highly Heuristic Decision Rules

Authors: Anqi Zhang, Wilson S. Geisler

arXiv

Visual search is a fundamental natural task for humans and other animals. We investigated the decision processes humans use in covert (single-fixation) search with briefly presented displays having we...

mental health psychology open access

Direct estimates of irreversibility from time series

Authors: Trevor GrandPre, Gianluca Teza, William Bialek

arXiv

The arrow of time can be quantified through the Kullback-Leibler divergence ($D_{KL}$) between the distributions of forward and reverse trajectories in a system. Many approaches to estimate this rely...

mental health psychology open access