Outcome of Antiretroviral Therapy and Its Predictors Among Clients Enrolled to Community Differentiated ART Service Delivery Model in Amhara Region, Ethiopia, 2024; Multi-Centered Retrospective Follow

Endometrial cancer is the sixth most common cancer among females, and the most prevalent gynecological cancer in high-income countries, including Canada., Rates of endometrial cancer are rising globally; in North America, the age-standardized incidence rate has increased from 35.8 cases per 100 000 people in 1990 to 86.6 cases per 100 000 people in 2019, reflecting the upsurge in the prevalence of key risk factors, particularly obesity, and an aging population. Most cases of endometrial cancer are diagnosed at an early stage, and total hysterectomy (removal of the uterus and cervix) with bilateral salpingo-oophorectomy and, often, lymph node assessment is the mainstay of initial management. Historically, hysterectomy in gynecological oncology has been performed using an open abdominal approach (laparotomy), but minimally invasive techniques such as conventional and robot-assisted laparoscopic approaches are increasingly being used. Robotic surgery is a relatively new minimally invasive technology that was developed to assist surgeons by providing improved visualization, greater precision, more accurate control of instrumentation, and improved ergonomics. There are, however, disadvantages to this surgical approach, including increased costs (acquisition and maintenance) and loss of tactile feedback. Studies have shown that both robotic hysterectomy (RH) and conventional laparoscopic hysterectomy (LH) provide clinical benefit for the management of endometrial cancer compared with open hysterectomy (OH), including decreased blood loss or transfusions, perioperative complications, length of hospital stay, and readmissions.– The surgical safety and clinical effectiveness of RH and LH appears comparable across most studies, and patients who undergo RH are consistently reported to have a shorter length of hospital stay than those who undergo LH.– Few studies comparing these surgical approaches for total hysterectomy have been conducted in Canada.– The objective of this study was to evaluate real-world acute health and health system outcomes of RH compared with LH and OH among patients living with endometrial cancer in Alberta, Canada.