Editorial: Interdisciplinary approaches to address mental health concerns during menopause.

Handedness refers to the preferential use of one hand over the other for daily routine tasks, classified into right-handers and left-handers, respectively known as dextral and sinistral, with a small fraction being ambidextrous or mixed-handed individuals. Right-handed individuals make up 90% of the entire population, evenly split between males and females. In contrast, left-handed individuals constitute a minority, comprising the remaining 10%, with a moderate sex difference of 6% men and 4% women. Most handedness studies conclude that the dominant depiction of right-handedness among humans is due to the localisation of language functions to the left hemisphere primarily, as it commands the movements of the right side of the body. The most prominent ‘Right-Shift Theory’ explicates that a genetic influence towards right-handedness is a consequence of one gene with two alleles. One of the alleles is the right-shift allele, which is responsible for the inheritance of right-handedness, whilst the other allele has no directional specialisation, invigorating left cerebral dominance, that is, left-handedness. Comparably, to describe the continuing distinguishable presence of left-handedness in the population, genetic scientists have elucidated that it is usually manifested as a recessive phenotypical trait among human and animal offspring. The genetic studies on handedness in the early 2000s suggested that the heritable component of left-handedness is estimated at up to 25%–40%. Gene models related to parental handedness patterns and their offspring’s handedness indicate a greater incidence of left-handedness when either one or both parents are left-handed.