Intranasal delivery of rapamycin via brain-targeting polymeric micelles for Alzheimer's disease treatment.

“Physical activity during pregnancy is positively associated with fetal metabolic health, birth outcomes, and enhanced neurocognitive development.” Regular physical activity, whether in the form of exercise or incorporated into the activities of daily living, is important for maintaining mental and physical health throughout the lifespan. Individuals who are more physically active have a lower prevalence of metabolic syndrome, cancer, and mood disorders, as well as higher bone density, healthier joints, and stronger muscles, tendons and ligaments. Despite the myriad benefits of physical activity, less than one quarter of the US adult population currently meets the United States Department of Health and Human Services’ combined-recommendation for aerobic exercise and muscle-strengthening activities (46.9% and 31.0% meet the recommendations for aerobic activity and muscle-strengthening activity, respectively).