Association Between Delivery Mode and Postpartum Psychiatric Conditions.
Authors: Kruger SL, Perlman N, Sherwin EB, Leggett CB, El-Sayed YY, Lyell DJ, Main EK, Wisner KL, Sultan P, Leonard SA, Panelli DM
Journal: Obstetrics and gynecology
mental health
psychology
open access
Abstract
Worldwide, there is increasing emphasis on developing novel drugs []. Drug clinical trials (DCTs), conducted in medical institutions prior to new drug registration and market approval, play a pivotal role in this process. These DCTs span Phase I through IV and involve both healthy volunteers and patient populations. By providing additional treatment options, DCTs are particularly valuable for individuals who lack effective therapeutic alternatives [–]. Nonetheless, significant challenges remain, such as difficulties in participant recruitment, insufficient enrollment, high dropout rates, and prolonged trial durations. The most critical challenge throughout the clinical trial process lies in effectively identifying, recruiting, enrolling, and retaining participants to ensure trial completion []. Globally, reports indicate that fewer than 5% of cancer patients participate in DCTs, and only about half of these trials achieve their target sample sizes [, ]. College students represent a key demographic for clinical trial recruitment. Compared to the general population, they generally possess higher educational levels and scientific literacy, making them both an ideal target group and an important focus in medical ethics considerations. The purpose of this study is to assess college students’ awareness of DCTs, identify influencing factors, and evaluate their willingness to participate. Based on the findings, corresponding educational and promotional measures will be proposed to address misconceptions and alleviate concerns, thereby fostering greater active participation and facilitating the wider promotion of DCTs among this demographic.