Enduring autism-like phenotypes and deregulated hypothalamic prosocial peptides after early-life exposure to indoor flame retardants in male C57BL/6 mice.
Authors: Kozlova EV, Gonzalez GM, Denys ME, Bishay AE, Gutierrez R, Reid J, Krum JM, Lampel G, Luvsanravdan N, Rabbani KM, Tu J, Campoy L, Anchondo LM, Luna CN, Olomi DS, Monarrez E, Carrillo V, Tran JD, Platt D, Korde Y, Chinthirla BD, Blaibel M, Kim S, Chompre G, Phillips AL, Stapleton HM, Henkelmann B, Schramm KW, Curras-Collazo MC
Journal: Journal of neuroendocrinology
mental health
psychology
open access
Abstract
Assessing dietary behaviors—including consumption of sugar‐sweetened beverages (SSBs) such as soda/pop (soda) and sports drinks—among adolescents is important given the long‐lasting and far‐reaching health effects of nutrition during this phase of life []. Furthermore, the Dietary Guidelines for Americans 2020–2025 recommend limited intake (< 10% of total daily calories) of added sugars []. Despite recommendations, during 2015–2018, 41% of youth aged 12–19 years consumed more than 15% of their total calorie intake in added sugars []; SSBs were a major source [, ]. Frequent consumption of SSBs has been associated with unhealthy weight gain, type 2 diabetes, cardiovascular disease risk, and cavities [, , , ]. In addition, socioeconomic factors, health behaviors, and the physical environment contribute to health outcomes []. In 2023, 15% of US high school students drank sugar‐sweetened soda daily, and 11% drank sports drink daily [] with variations by grade [], sex, and race and ethnicity [, ]. Although the overall prevalence of daily consumption has decreased (soda: 34% in 2007, sports drink: 14% in 2015) [], frequent consumption of these beverages continues to jeopardize high school students' health. For example, recent national data show that, among those aged 12–19 years, 22% have obesity and 56% have cavities []. Furthermore, evidence suggests adolescents might employ unhealthy behaviors as a way of coping with life stressors []. The developing adolescent brain is particularly susceptible to the effects of stress [, , ], and stress during adolescence has been associated with unhealthy eating behaviors [, ]. More specifically, experiences of bullying or other violence at school have been associated with soda consumption []. Also, adolescents who experienced housing instability have an increased risk for unhealthy behaviors such as substance abuse and risky sexual health behaviors []. Better understanding the relationship between life stressors and unhealthy behaviors—such as soda and sports drink consumption—among adolescents could help identify potential strategies to improve their diet and health.