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Incidence of misophonia, associated auditory symptoms and sensory processing profiles in university students in Turkey: a comparative study of clinical, subclinical and control groups.

Authors: Şahin Kamişli Gİ, Ülkeroğlu Ö, Karataş S, Durusu AN
Journal: The Journal of laryngology and otology
mental health psychology open access

Abstract

The rate of posthospitalization adverse drug events (ADEs) among older adults has been estimated at 4% to 37%, with recent rates of 5% to 6% found in 2 large medication management clinical trials. Posthospitalization ADEs can result in serious morbidity or death. Furthermore, they are a frequent cause of readmission in older adults. Older adults disproportionately experience posthospitalization ADEs due to predisposing comorbidities such as kidney and cognitive impairment and burdensome medication regimens in terms of polypharmacy, dosing complexity, and ADE risk. These issues are compounded in the immediate postdischarge period by increased morbidity and care discontinuity. Prior research shows that up to one-quarter of postdischarge ADEs are preventable. Furthermore, several teams demonstrated that pharmacy-centric transitions-of-care (TOC) interventions had substantial potential to reduce postdischarge ADEs. Nonetheless, pharmacist-led TOC interventions remain scarcely used. Lack of use may be attributable to the size of prior studies, which necessitated focus on process improvements rather than clinical and financial end points such as health care utilization. To convince hospital and health system leaders to fund pharmacist-led TOC interventions, we sought evidence that these interventions would impact health care utilization. Thus, we conducted a pragmatic trial with sufficient power to detect an effect of pharmacist-led TOC interventions on health care utilization after hospital discharge.