GLP-1 receptor agonists and risk of suicide or suicide attempts - A nationwide cohort and self-controlled case series study.
Authors: Stanislaus C, Winther-Jensen M, Stanislaus S, Osler M, Coello K, Vinberg M
Journal: Molecular psychiatry
mental health
psychology
open access
Abstract
Eating disorders (EDs) disproportionately affect adolescents and young adults (AYAs), with incidence rates rising since the COVID‐19 pandemic (Gilsbach et al. ; Hartman‐Munick et al. ; Trafford et al. ). While treatment programs initially transitioned to remote delivery as a pandemic necessity (Murphy et al. ), online therapy remains widespread post‐pandemic (Ferguson et al. ). Evidence suggests comparable ED symptom improvements whether treatment is online or in‐person (Drury et al. ; Levinson et al. ; Ortiz et al. ; Raykos et al. ; Steiger et al. ). However, patient perspectives about online therapy vary. Some studies report neutral to positive perceptions (Linardon et al. ), while others document stronger preferences for in‐person sessions (Lewis et al. ; Stewart et al. ) or identify both advantages and disadvantages (Leder et al. ). Despite guidelines for online cognitive‐behavioral therapy (CBT) for EDs (Couturier et al. ; Murphy et al. ; Waller et al. ), its acceptability among AYAs remains insufficiently explored, particularly regarding specific CBT interventions. Certain interventions (e.g., education) may translate more effectively to online formats than others (e.g., open weighing). This study examined AYAs' perceptions of online CBT for EDs—specifically assessing its perceived value, comfort level, and satisfaction—while also determining whether participants viewed individual CBT interventions as equally effective online versus in‐person. Given that adolescents may prefer in‐person over online therapy (Lewis et al. ; Stewart et al. ), we hypothesized that AYAs would perceive in‐person CBT as more valuable and comfortable than online CBT. Nevertheless, since most adolescents find online therapy acceptable despite such preferences (Ahmadiankalati et al. ; Pretorius et al. ; Stewart et al. ), we predicted that AYAs would report satisfaction with online CBT. Given evidence that adolescents reported stronger preferences for in‐person therapy than their parents (Stewart et al. ), we hypothesized that favorable attitudes toward online therapy would be negatively associated with younger age. We also predicted that the proportion of online sessions would positively correlate with favorable attitudes. Finally, based on evidence supporting the acceptability of online CBT for EDs (Ahmadiankalati et al. ; Pretorius et al. ), we expected participants to rate CBT interventions as equally effective online versus in‐person.