A deep learning model to dynamically predict cancer-associated thromboembolism in large-scale healthcare systems.
Authors: He T, Zheng C, La J, Pham D, Jafari O, Strampe J, Dulberger K, Ramos-Cejudo J, Gaziano JM, Do NV, Chitalia V, Ravid K, Li A, Fillmore NR
Journal: NPJ digital medicine
mental health
psychology
open access
Abstract
Malnutrition is one of the most serious public health concerns affecting at least half of children under five years of age in developing countries [–]. Malnutrition refers to deficiencies, excesses, or imbalances in energy and/or nutrient intake, or impaired nutrient utilization, and includes undernutrition, overweight, and obesity []. In this paper, we considered under-nutrition and malnutrition equivalently. The indicators of childhood undernutrition involve stunting, underweight, and wasting. Stunting, underweight, and wasting occur in children under five years who are below 2 standard deviations from the median height-for-age, weight-for-age, and weight-for-height, respectively, as defined by the World Health Organization (WHO) Child Growth Standards []. Malnutrition in early childhood is associated with functional damage in adult life, as malnourished children are physically and intellectually less productive when they become adults [, ]. Children who are malnourished tend to have an increased risk of morbidity and mortality, and often suffer from delayed mental development, poor school performance, and reduced intellectual achievement []. According to the UNICEF–WHO–World Bank Joint Child Malnutrition Estimates, in 2024, the global prevalence of stunting (height-for-age), underweight (weight-for-age), and wasting (weight-for-height) among children under five years was 23.2%, 12.2%, and 6.6%, respectively [–]. According to recent reports for 2024, approximately 150.2 million children under five years of age are stunted, 42.8 million are wasted, and 35.5 million are underweight worldwide []. In 2024, an estimated 4.9 million children died before reaching their fifth birthday worldwide []. Moreover, in 2024, 51% of children under five affected by stunting lived in Asia, and 43% lived in Africa []. For wasting, WHO reported that in 2020, 70% of affected children lived in Asia and 27% in Africa []. According to the report for 2025 published by the International Food Policy and Research Institute (IFPRI), Bangladesh is ranked as the 85th hunger-prone country out of a total of 123 countries based on the Global Hunger Index []. Malnutrition remains a major public health concern in Bangladesh, with more than half of the population affected, including approximately 450,000 children with severe acute malnutrition and nearly two million with mild acute malnutrition []. Children’s nutritional status has gradually improved over the past decades: the prevalence of stunting among under-five children declined from 51% in 2004 to 43% in 2007, 41% in 2011, 36% in 2014, 31% in 2018, and 24% in 2022; underweight decreased from 43% in 2004 to 41% in 2007, 36% in 2011, 33% in 2014, and 22% in both 2018 and 2022; similarly, wasting showed some fluctuation but an overall decline from 15% in 2004 to 17% in 2007, 16% in 2011, 14% in 2014, 9% in 2018, and 11% in 2022 [–]. However, Bangladesh still has a higher than acceptable rate of malnutrition, with 10% of the population being underweight and 30% of the population being stunted [–]. The government of Bangladesh has strongly committed to achieving the 2030 Sustainable Development Goals (SDGs). End hunger, achieve food security, improve nutrition, and promote sustainable agriculture; all these nutrition-related factors are included in the Sustainable Development Goals (SDGs) []. The country won’t achieve its SDG goal of reducing child mortality if undernutrition is not properly controlled []. To plan and implement effective community-level interventions, the health system must identify malnutrition early.