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Qualitative assessment of the clinical meaningfulness of MDS-UPDRS part III items in early-stage Parkinson's.

Authors: Cleanthous S, Barker RA, Biagioni M, Dexter DT, Simuni T, Morel T
Journal: Journal of Parkinson's disease
mental health psychology open access

Abstract

Capturing prey is fundamental to animal survival and has been a central focus in studies of the evolution of morphological and physiological traits (; ). Predation typically involves a sequence of dynamic interactions – detection, evaluation, pursuit, and subjugation – resulting in either prey capture or escape (; ). Although the strength of selective forces acting on predators and prey may differ, both exert strong influences on individual fitness. Consequently, predators have evolved sophisticated behavioral strategies to maximize prey capture efficiency. Foraging strategies range along a continuum from ambush to active pursuit. Predators that chase moving prey must process complex environmental cues while executing precise movements to ensure successful capture. For example, larval zebrafish visually detect prey and converge their eyes to form a small binocular strike zone in front of the head (; ). Subsequently, they target their prey by closing the distance along the body axis and attack once the prey enters the strike zone (; ). Dragonflies employ an interception strategy in which they approach the prey from below, within the prey's blind spot, while stabilizing the prey's retinal image through predictive head rotations (). In contrast, cuttlefish flexibly alternate between rapid tentacle ejection and full-body jump attacks depending on prey size and movement: small, fast-moving prey are typically captured by tentacle strikes, whereas prey like larger crabs elicit the jump strategy (). Across taxa, vision serves as one of the most powerful and effective sensory modalities for prey capture, enabling predators to detect, pursue, and capture prey over a wide range of sizes and ecological contexts (; ; ). The outcome of a predator's attack depends not only on the accuracy and velocity of the strike () but also on the evasive and escape behaviors of the prey (; ; ; ). When one participant – predator or prey – possesses superior speed, the other must compensate through enhanced locomotor performance (e.g. acceleration and maneuverability) or through behavioral strategies such as anticipatory positioning, stealth, or responsiveness (; ). Thus, understanding the determinants of predator–prey encounter outcomes requires simultaneous analysis of the movement dynamics of both parties, yet such studies remain relatively rare. Lake Tanganyika in East Africa harbors a highly endemic freshwater fauna and exhibits well-defined predator–prey relationships (). More than 250 species of cichlids inhabit this lake, exhibiting extraordinary trophic diversification (; ; ; , ). These include aufwuchs feeders, planktivores, detritivores, shrimp eaters, benthic invertebrate feeders, piscivores, and scale eaters (; ; , ; ). Among these trophic types, the scale-eating cichlids occupy a high trophic position, feeding on scales removed from the bodies of other fishes (). The shallow-water species is particularly well known and has been reported to attack 38 species of fish, primarily aufwuchs feeders such as and (). Therefore, plays a key ecological role as a predator influencing the fish community structure in Lake Tanganyika.