Bilateral transcutaneous auricular nerve stimulation promotes motor function recovery after stroke: A randomized controlled trial.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder causing significant cognitive decline and memory impairment. Characterized by accumulation of cerebral amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs), which lead to neuronal damage and brain atrophy, AD is the most prevalent form of dementia, and is becoming increasingly common due to rising life expectancies., Although there is currently no cure for AD, the identification of modifiable risk factors offers promising opportunities for delaying onset or preventing development. Symptoms of depression are commonly observed in individuals with AD, particularly in its early stages. Research suggests that depression may act both as a risk factor for and an early indicator of AD. The co‐occurrence of depressive symptoms and cognitive decline complicates both diagnosis and treatment, often accelerating disease severity and progression. Our previous work on dietary fiber and protein identified that high dietary protein intake may have a protective effect on brain Aβ burden in older adults. Further evidence indicates that dietary fiber intake can reduce inflammation, regulate gut health, and enhance metabolic function: key processes in preventing neurodegenerative conditions. Fiber supports the growth of beneficial gut microbiota, which play a significant role in brain health through the gut–brain axis. This axis influences serotonin production and modulates inflammatory pathways implicated in both depression and AD.,