PACM-03 TUMOR–BRAIN CROSSTALK DRIVES NEURAL MICROENVIRONMENT REMODELING AND PROMOTE DEMYELINATION IN BRAIN METASTASES.

Bangladesh witnessed a violent mass uprising led by university students protesting the reinstatement of a controversial quota system for civil service positions in early July 2024. It started after the High Court’s decision to reinstate the quota system, which had been abolished in 2018 following extensive protests, and triggered widespread unrest among university students, primarily. This movement, known as the anti-quota movement, became one of the most violent episodes in Bangladesh’s history since the Liberation War of 1971, ultimately contributing to the ousting of the The term "quota" typically refers to a system of political or social allocation used to ensure representation for various communities, such as ethnic, religious, or gender (male and female), within a government or organization. In 1972, the Bangladesh government introduced a quota system that reserved a percentage of government jobs for the descendants of those who fought in the 1971 Liberation War. Under this system, 44% of government jobs were based on merit, while the remaining 56% were reserved for specific groups: 30% for descendants of freedom fighters, 10% for women, 10% for candidates from underdeveloped districts, 5% for ethnic minorities, and 1% for individuals with disabilities. This quota system was abolished in October 2018 after widespread protests. The current anti-quota movement is focused on abolishing the 30% quota for descendants of freedom fighters, while still supporting the reservation of jobs for ethnic minorities and people with disabilities. The United Nations (UN) reported that at least 1400 people were killed, more than 11,700 people were arrested and detained. The casualties included innocent civilians, children, protesters, bystanders, journalists, and members of the security forces. The majority of these deaths were attributed to the actions of security forces, including the Police, Rapid Action Battalion (RAB), Border Guard Bangladesh (BGB), and affiliated groups of the ruling Awami League, such as the youth wing (Jubo League), volunteers wing (Swechchhasebak League), and student wing (Chhatra League). These groups were reported to be armed with illegal firearms and crude weapons, contributing to the violence that has since been labeled the ‘July Massacre.’ Along with deaths, it causes eye injury to more than 1300 persons, and 630 persons required eye surgery.