Atypical parkinsonian syndromes in French Guiana: Similarities and differences with Caribbean variants.

The human skin operates as the body's primary defence against external hazards, providing physical, chemical, and immunological protection []. Covering an area of ~ 2 m, it is distributed in microenvironments inhabited by various microorganisms that comprise the skin microbiota. In homeostasis, the skin microbiota benefits from lipids, salts, and proteins secreted by the skin, using them as a food source. In return, it aids in the process of integrity and repair of the host's skin barrier—a mutually beneficial relationship [, , ]. Skin microbiota plays a strong role in the immune system, where innate and adaptive immune responses for tissue repair and preservation are regulated by specific microbiota functions []. When the diversity and abundance of commensal microorganisms are unbalanced, the relationship with the host can become non‐symbiotic, resulting in dysbiosis. Aspects, such as infections, itching, redness, and dryness are associated with microbiota imbalance. In more severe cases, dysbiosis can trigger or worsen inflammatory dermatoses, such as acne vulgaris, atopic or seborrheic dermatitis, rosacea, and psoriasis [, , ]. Understanding the causes of dysbiosis is essential to accessing effective treatments. In this scenario, strategies for restoring diversity and relative abundance to rebalance the microbiome have been increasingly explored in the literature [, , , , ]. The approach that previously involved promoting asepsis in dysbiotic conditions is now focused on restoring the resident microbiota, responsible for various processes that maintain skin integrity and protect it against pathogens [, ].