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Multi-metric evaluations of acute psychedelic effects on fMRI brain entropy.

Authors: McCulloch DE, Olsen AS, Ozenne B, Larsen K, Stenbæk DS, Armand S, Madsen MK, Knudsen GM, Fisher PM
Journal: Nature communications
mental health psychology open access

Abstract

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), responsible for the COVID-19 pandemic, causes infectious respiratory disease and affects anyone, manifesting in mild or severe forms. Transmission, which occurs through the respiratory route, via droplets or aerosols, is related to high transmissibility. In this context, several global initiatives were developed and implemented to contain the pandemic. Vaccines, one of the initiatives launched in 2020, represent indispensable tools in the fight against COVID-19, as they guarantee individual and collective prevention of severe forms of the disease by sensitizing the body’s immune system to recognize and create antibodies against the virus. However, they can cause mild or severe side effects, which tend to disappear within a few days. Immunization is essential in controlling the spread of the COVID-19 pandemic. The World Health Organization led the COVID-19 Vaccines Global Access Center (COVAX Facility initiative), which optimized the timeline for vaccine production and licensing. Furthermore, it played a leading role in developing a toolkit with guidelines, training, and information to support vaccine distribution programs. Alongside these efforts, randomized controlled trials were conducted to verify vaccine safety and efficacy.