Non-pharmacological interventions for managing fatigue across the lifespan of people living with chronic musculoskeletal conditions: a scoping review.

Maternal asthma is associated with increased risk of offspring asthma in early childhood more than paternal asthma, but phenotype-specific familial risk is poorly understood. Our findings indicate a greater association with maternal than paternal asthma, especially for early-onset persistent asthma. The maternal effect persists regardless of parental atopy. Early-onset transient asthma appears less influenced by familial risk and may reflect viral wheeze. Family history, particularly maternal asthma, may help identify children at increased risk of persistent asthma. Recognition of phenotype-specific familial patterns may help identify children at increased risk of persistent asthma and inform future approaches to monitoring and risk stratification.