Evaluating clinical associations of immediate post-traumatic headache: a prospective multicenter study.

It is estimated that diabetes will affect approximately 1.3 billion people by 2050. Despite evidence-based guidelines advocating comprehensive management strategies, a persistent gap between clinical recommendations and actual implementation remains a critical barrier to improving outcomes. For instance, China has the largest number of adults with diabetes worldwide. However, only 32.9% of patients with diabetes in China have received treatment, among whom only 50.1% have achieved effective glycemic control. Similarly, a global pooled analysis encompassing data from 200 countries and territories estimated that 59% of adults aged 30 years or older with diabetes did not receive treatment in 2022. Furthermore, a cross-sectional analysis including pooled data from 55 national surveys showed that less than 10% of adults with diabetes were comprehensively treated to guideline standards based on 6 core clinical treatment indicators. These findings underscore systemic challenges in translating knowledge into practice. Addressing this challenge requires multifaceted strategies, and continuous education for health care professionals is fundamental. Conventional training programs predominantly relying on passive knowledge dissemination are not sufficient to foster long-term adherence to guidelines in chronic disease management. Although innovative approaches—such as the use of online platforms—have enhanced the flexibility and efficiency of medical education, their inability to simulate actual clinical interactions and cultivate empathy may hinder the development of patient-centered care skills. Therefore, effective implementation of training programs that integrate experiential learning with adaptable online methods is needed. To address these limitations, we designed the Chinese Endocrinologists Health Education Study (CREATION), a multicenter, cluster randomized clinical trial to evaluate a novel role-playing–based intensive training program for physicians managing patients with type 2 diabetes. This intervention uniquely combines immersive offline physician-as-patient simulation with sustained digital reinforcement through a nationwide standardized care platform, with the dual objectives of enhancing physicians’ adherence to clinical practice guidelines and improving metabolic control outcomes among their patients. Accordingly, CREATION was designed to evaluate whether a role-playing–based intensive training program for physicians could improve metabolic outcomes among patients with type 2 diabetes compared with regular training.