Human-AI Interaction With AI-Assisted Tumor Overlays in Pediatric Whole-Body Magnetic Resonance Imaging: Exploratory Reader Study.

Suicide risk in adolescence fluctuates over short time scales and is shaped by affective and contextual processes []. Continuous naturalistic assessment of psychophysiological markers may improve understanding of proximal risk states and inform timely intervention strategies []. High-frequency heart rate variability (HF-HRV; 0.15‐0.40 Hz), reflecting parasympathetic nervous system activity, has been linked to emotion regulation capacity and affective flexibility []. Lower resting HF-HRV and altered HF-HRV reactivity have been associated with suicidal ideation and behavior beyond depressive and anxiety symptoms [-]. However, most studies linking HF-HRV to suicide risk have relied on laboratory or cross-sectional designs. Ambulatory monitoring may better capture real-world fluctuations in suicidal ideation, which often emerge outside clinical settings and may be influenced by sleep and daily demands [,]. Chest-worn electrocardiogram (ECG) sensors provide superior signal quality compared with wrist-based photoplethysmography devices [], yet no prior studies with adolescents used chest-worn devices for more than one week. Chest-worn devices may pose feasibility challenges including discomfort, visibility under clothing, interference with daily activities, and susceptibility to user error, especially among distressed adolescents. Hence, the long-term feasibility for their use in adolescents receiving intensive psychiatric care remains unclear. This study evaluated the feasibility of continuous HF-HRV monitoring over 2‐3 weeks using a research-grade chest-worn ECG sensor in adolescents receiving intensive outpatient treatment for depression and suicidality. Our target benchmarks, specified a priori, were ≥75% for both compliance (sensor wear time) and data quality (valid HRV data). We also examined whether feasibility varied over time, by sleep and wake periods, or by school attendance.