Temporal trends in post-cardiac arrest brain injury research: a bibliometric analysis of evolving priorities and translation gaps.

Hidradenitis suppurativa (HS) is a chronic, inflammatory, and recurrent disease of the pilosebaceous unit that primarily affects intertriginous areas, including the axillae, groin, gluteal, and anogenital regions. It is characterized by painful nodules, abscesses, sinus tract formation, and scarring, frequently leading to substantial physical discomfort, functional impairment, and long-term disability. The epidemiology of HS demonstrates considerable geographic variability depending on the studied population and diagnostic methodology. In Europe, prevalence estimates around 1.0%, in the United States, HS prevalence seems to be higher, while in Asian countries reported prevalence ranges from 0.14% to 0.19%. Moreover, important sex-related differences have been described. In most European and North American populations, HS predominantly affects females, with reported female-to-male ratios ranging from approximately 2–3:1, whereas in some East Asian populations males appear to be more frequently affected. HS most commonly develops in young adults, with disease onset typically occurring between 18 and 30 years of age. It is generally accepted that the disease remains underrecognized and is often associated with significant diagnostic delay, contributing to disease progression and cumulative burden., The pathogenesis of HS is complex and multifactorial, involving genetic predisposition, dysregulated immune responses, and environmental factors. Importantly, HS is increasingly recognized as a systemic inflammatory condition associated with multiple comorbidities, including metabolic syndrome, cardiovascular disease, inflammatory bowel disease, and spondyloarthropathies., However, beyond its somatic manifestations, HS imposes a profound psychosocial burden that markedly affects patients’ quality of life (QoL), often exceeding that observed in other dermatological disorders. Patients with HS frequently experience intense pain, pruritus, malodor, and drainage, as well as lesions located in intimate body areas, which significantly impair social functioning, interpersonal relationships, and sexual health., These factors contribute to stigmatization, social withdrawal, and reduced occupational productivity. Consequently, psychiatric comorbidities are highly prevalent in this population, with depression and anxiety reported in a substantial proportion of patients., Notably, previous studies have demonstrated that over 20% of individuals with HS exhibit clinically relevant depressive and anxiety symptoms, which are strongly associated with disease severity, subjective symptom burden, and impaired QoL. Beyond conventional psychiatric comorbidities such as depression and anxiety, increasing attention has recently been directed toward disturbances in higher-order emotional processing in patients with chronic inflammatory diseases. Difficulties in recognizing, interpreting, and expressing emotions may contribute to maladaptive coping strategies, impaired interpersonal functioning, and reduced psychological adaptation to chronic illness.