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ASC-emotion: A privacy-aware dataset for analysing emotional dysregulation and engagement in children with Autism().

Authors: Turabee ZB, Brown DJ, Mahmud M, Oikonomou A, Rahman MA, Burton A, Shopland N, Clarke D, Gray F
Journal: MethodsX
mental health psychology open access

Abstract

Bipolar disorder is a chronic, recurrent mood disorder defined in the DSM−5-TR by episodic mania (bipolar I disorder) or hypomania and depression (bipolar II disorder) . The prevalence of bipolar spectrum disorders in the U.S. adult population is approximately 4%, corresponding to about fifteen million adults . In addition to mood symptoms, people with bipolar disorder often suffer from persistent cognitive impairment in attention, memory, and executive function domains, conferring additional functional burdens . Features such as cognitive deficits, fluctuating insight, and variable treatment adherence are especially relevant when bipolar disorder co-occurs with complex medical conditions such as cancer, or when cancer burden and treatment, in turn, contribute to worsened mental health. Reviews of severe mental illness (SMI) and cancer have shown that people with bipolar disorder and other mental illnesses experience barriers to health care that extend into oncology, resulting in poorer access to cancer screening and treatment, conferring elevated risk for mortality . Despite growing attention to psychological distress in oncology, bipolar disorder remains under-studied and under-recognized; large psycho-oncology datasets frequently rely on composite categories such as “mood disorder” or “serious mental illness” without specific considerations for bipolar disorder , . Although bipolar disorder is both a mood disorder and a serious mental illness, it is distinctive in the symptom burden it confers from other mood disorders like major depression. To improve outcomes, clinicians providing care to people with bipolar disorder must consider potential impacts on cancer care, as well as how cancer and cancer care may affect mood stability. This narrative review synthesizes information on bipolar disorder in oncology for mental health clinicians and oncologists treating people with co-occurring bipolar disorder and cancer. People with cancer have higher prevalence rates of psychiatric disorders than the general population . In a population-based cohort of 459,542 individuals with cancer, the cumulative burden of five major psychiatric disorders, including bipolar disorder, was associated with a markedly increased risk of self-harm and years of life lost compared with cancer patients without such diagnoses . Evidence on whether bipolar disorder increases the risk of developing cancer is mixed but suggests a modest elevation; for instance, a U.S. sample of patients with schizophrenia and bipolar disorder combined showed a 2.6-fold higher cancer risk compared with the general population .