Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias.
Authors: Silverstein SM, Zolnik T, Larkum M, Thompson JL
Journal: Current research in neurobiology
mental health
psychology
open access
Abstract
The tibiofemoral joint must simultaneously provide stability and a wide range of motion to support weight-bearing, gait, and rotational activities. This stability arises from the interplay between osseous morphology, articular cartilage, menisci, static ligamentous restraints, and dynamic muscular control [-]. Variations in tibial plateau geometry, such as slope and concavity, influence load distribution and ligament strain and have been linked to altered knee biomechanics and injury risk [-]. Tibial plateau fractures disrupt this finely tuned system and endanger both joint congruence and soft-tissue stabilizers. They account for approximately 1-2% of all fractures and constitute a heterogeneous group of injuries that range from low-energy split-depression patterns in osteoporotic bone to high-energy bicondylar fractures with severe comminution and soft-tissue compromise [-]. Population-based data from a CT-validated series reported an annual incidence of 10.3 per 100,000 inhabitants, with a predominance of high-energy injuries among younger men and an increasing incidence of low-energy fragility fractures among older women []. Motor-vehicle collisions and high-velocity trauma are especially associated with complex bicondylar and posteromedial fracture patterns [-]. Beyond the bony injury, tibial plateau fractures frequently involve the menisci, cruciate and collateral ligaments, and the posterolateral corner. Radiographic parameters such as condylar widening and articular depression are associated with a higher probability of associated soft-tissue damage, highlighting the limitations of plain radiographs in fully characterizing the injury [,]. Cross-sectional imaging refines this assessment: CT improves depiction of fracture morphology and guides preoperative planning, whereas MRI better identifies meniscal and ligamentous injuries that may alter the surgical strategy [,].