Prazosin-Related Reductions in Daily Craving Mediate Treatment-Related Daily Alcohol Use Outcomes in Alcohol Use Disorder.
Authors: Wemm S, Hart R, Hermes G, Harvanek Z, Sinha R
Journal: Biological psychiatry global open science
mental health
psychology
open access
Abstract
Personal values are those aspects that individuals consider important and meaningful in their lives []. In research, values have primarily been conceptualized from two distinct theoretical approaches. First, Schwartz's Theory of Basic Human Values (TBHV; []) defines values as beliefs about broad desirable objectives that function as guiding principles for decision-making and behavior. This theory organizes 19 values in a circular structure based on compatible and conflicting motivations: openness to change, self-enhancement, conservation, and self-transcendence. Second, Acceptance and Commitment Therapy (ACT) positions values as a central construct within the Hexaflex model of psychological flexibility []. Within this framework, values are conceptualized as freely chosen, verbally constructed life directions that are expressed through ongoing and evolving patterns of action []. While Schwartz's theory focuses on the underlying motivational content of values, ACT focuses on formal processes related to how individuals clarify their values and act in accordance with them in daily life, independently of their specific content, which is known as valued living. Recent research indicates that valued living may be a stronger predictor than the motivational content of values for mental health outcomes []. Higher levels of valued living have been associated with lower depressive and anxious symptomatology [] and with higher levels of well-being and meaning in life [,]. Moreover, valued living has been identified as a relevant factor in resilience among university students []. Together, these findings support the relevance of situating valued living within a broader model of mental health. The sustainable mental health framework proposed by Bohlmeijer and Westerhof [] is particularly useful in this regard, as it conceptualizes mental health not only as the absence of psychological distress but also as the presence of well-being and the capacity to adapt to life challenges over time. From this perspective, mental health is shaped by the interplay between psychological resources (e.g., strengths, positive relationships, and meaning) and psychological barriers (e.g., cognitive biases, dysfunctional beliefs, and avoidance) that either support or hinder adaptation. Within this framework, valued living may function as a psychological resource that provides meaning and direction, thereby supporting individuals’ capacity to adapt to life challenges while maintaining psychological well-being over time. As such, valued living may represent a relevant target for psychological interventions aimed at promoting sustainable mental health.