Physical function impacts hearing without mediation from systolic blood pressure.

Sexual function is influenced by a complex interaction of biological, psychological, and social factors such as previous sexual experiences, emotional relationships, medication use, and mood state. The presence of sexual dysfunction can negatively affect not only intimate relationships but also general health and well-being, leading to a substantial decline in quality of life. To evaluate this multifactorial and subjective health issue, standardized tools such as the have been developed and validated in multiple languages. Sexual dysfunction has been previously studied in rheumatic and immunological disorders, where pain, vascular changes, chronic inflammation, psychological stress, and medication often contribute to impaired sexual health. Pain, limited physical activity, and anti-inflammatory drugs have been identified as major contributors to sexual dysfunction in males with rheumatoid arthritis. Similarly, in psoriatic arthritis, glucocorticoid exposure, musculoskeletal involvement, and longer disease duration have been associated with a higher prevalence of sexual dysfunction. Approximately one in five patients with psoriatic arthritis perceive their disease as having a negative impact on sexual activity. Elevated C-reactive protein levels and chronic back pain correlate with reduced sexual function in ankylosing spondylitis, while psychological distress and anxiety further exacerbate this impairment. Collectively, these findings indicate that sexual dysfunction in rheumatic diseases arises from both physiological and psychosocial mechanisms. Familial Mediterranean fever (FMF) is the most common autosomal recessive autoinflammatory disease, prevalent among populations from the Mediterranean basin and the Middle East. The disease typically initiates in childhood and is characterized by recurrent attacks of fever, peritonitis, pleuritis, arthritis, or erysipelas-like skin lesions. Although patients are generally asymptomatic between attacks, subclinical inflammation often persists, contributing to chronic vascular and systemic effects that may impair daily functioning and overall quality of life.