Large language models in respiratory care: safety and clinical integration.

Without effective antibiotics, even routine surgeries could become dangerously risky to perform. The Global Antibiotic Resistance Surveillance Report 2025 () shows a 40% increase in antibiotic resistance for the monitored antibiotics between 2018 and 2023. Using antibiotics optimally and reducing the need to use them through adequate hand hygiene can help slow antibiotic resistance (). In addition, for children, interventions that aim to improve hand hygiene have been shown to significantly reduce some illness-related school absences (). Therefore, empowering children with knowledge of hygiene and responsible use of antibiotics could help alleviate some absences related to illness, reducing antibiotic resistance but also promoting more responsible use of antibiotics as they become adults (). When designing educational activities for children, it is important that they are engaging. Games have the potential to create engaging and enjoyable experiences (). However, educational games are sometimes criticized for being “chocolate-covered broccoli" () by attempting to make inherently unappealing educational content more engaging by adding superficial elements of fun, such as points, rewards. Adding entertainment as a layer over the educational content does not always result in meaningful engagement. Players, as a result, perceive the disconnect between the “chocolate" (game-like features) and the “broccoli" (educational content). Therefore, in addition to learning, making sure that the player finds the experience of playing the game enjoyable needs to be considered when using the game, as the fact that the games are enjoyable is the reason why a game would be chosen over a less expensive non-gaming learning environment (). In addition, according to Csikszentmihalyi et al. (), “learning has to be engaging and rewarding for students to learn" (p. 9). This has been linked to many benefits in education, such as students obtaining higher grades, being less likely to give up, and having higher completion rates (, ).