Translation and validation of the functional assessment of cancer therapy-endometrial cancer (FACT-En) version 4 quality of life instrument into Thai language.

Epilepsy is one of the few chronic medical conditions consistently associated with an increased risk of suicide across the lifespan, including among children and adolescents [, ]. This elevated risk is particularly pronounced during adolescence, a critical developmental period marked by rapid biological, psychological, and social transitions that may heighten vulnerability to emotional distress and maladaptive coping [, ]. For adolescents with epilepsy, these normative developmental challenges are compounded by the burden of a chronic neurological condition, creating a context in which suicidality may emerge or be exacerbated []. Globally, suicide is the fourth leading cause of death among young people aged 15–19 years, underscoring the public health significance of suicidality in this age group []. In individuals with epilepsy, the risk of suicidal ideation and behaviour appears to be higher than in the general population []. Epidemiological studies indicate that up to 20% of children and adolescents with epilepsy experience suicidality, substantially exceeding rates observed in community samples without epilepsy [, ]. A limited but growing body of research has examined suicidality in paediatric epilepsy populations. For example, studies have reported that children and adolescents with epilepsy are significantly more likely to exhibit self-injurious behaviours and suicidal ideation compared with age-matched controls, highlighting the elevated psychological vulnerability in this group []. Psychiatric comorbidities, particularly depressive and anxiety disorders, are common among young people with epilepsy and have been consistently associated with increased suicide risk [, , –]. In addition, several illness-related factors, including poor seizure control, polytherapy with antiepileptic drugs, and early age at epilepsy onset, have been implicated as potential contributors to suicidality []. Psychosocial factors such as coping strategies and perceived social support may further shape how adolescents with epilepsy respond to illness-related stressors, although findings across studies have been inconsistent and context dependent [–]. In low- and middle-income countries (LMICs), including many in sub-Saharan Africa (SSA), adolescents with epilepsy face additional contextual challenges such as stigma, limited access to specialist care, treatment gaps, and social exclusion, all of which may exacerbate psychological distress and impede access to mental health services [–]. In Uganda, cultural stigma and legal frameworks that criminalise suicide further complicate help-seeking and community responses to suicidality []. Despite these intersecting vulnerabilities, empirical evidence on suicidality among adolescents with epilepsy in African settings, and particularly in Uganda, remains scarce.