Cumulative mild stress during early life alters prefrontal astrocytic proteins and elevates peripheral S100B in young adult mice.

The Brazilian public health system, known as the ,, is a universal, comprehensive and equitable publicly funded health system that is primary care-centered. Since the implementation of the National Primary Health Care Policy in 2006, the predominant primary care model in Brazil is the Family Health Strategy []. evidenced to perform, on average, five points better than traditional public healthcare model according to the Primary Care Assessment Tool []. It emphasizes continuity, comprehensiveness, and a community- and family-orientated approach to care [, ]. It is organized through multiprofessional teams, responsible for coordinating care to approximately 3,500 people across health system. The Family Health Strategy emphasis on community and family orientations is reinforced through the community health worker’ home visits and collaborations with schools and community-based organizations []. Therefore, primary care not only reduces health inequalities among its users [] but also has the potential to influence societal attitudes within the geographically defined areas covered by primary care teams. Considering that Brazil comprises 5,570 municipalities, of which nearly 69% have populations under 20,000 and 23% have up to 5,000 inhabitants, in small municipalities, a single primary care team is often responsible for supporting care of the entire municipality population []. Despite of Family Health Strategy promoting equitable healthcare, there are evidences that discrimination at health care level still exists, more frequently against women [], people with black/brown skin color, those who utilize health services more frequently, individuals with lower educational attainment [, ] and those without private health insurance []. Discrimination occurs when individuals (i.e., interpersonal interaction) or institutions (i.e., organizational practices or societal discrimination) engage in unfair treatment toward socially subordinated groups, such as sexual orientation minorities, reinforcing societal hierarchies of dominance and subordination [].