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Intracranial Candida parapsilosis infection occurring 2 years after burr-hole drainage for chronic subdural hematoma: a case report.

Authors: Li J, Lin S, Liu W, Li P, Luo L
Journal: British journal of biomedical science
schizophrenia mental health open access

Abstract

Left ventricular assist device (LVAD) implantation is an established therapy in end-stage heart failure. Despite improved technologies and perioperative management, complications, including bleeding, thromboembolic events, infections, and end-organ injury, remain high. Acute right heart failure (RHF) affects 20%-40% of patients after LVAD implantation. Right heart failure post-LVAD surgery involves multifactorial mechanisms, with right ventricular function being highly sensitive to loading changes. Cardiopulmonary bypass (CPB) priming affects physicochemical and homeostasis balance. While crystalloids cause dilution, blood-based priming with fresh frozen plasma (FFP) and red blood cells (RBCs) aims to preserve oncotic pressure, reduce haemodilution, and may decrease bleeding and postoperative organ dysfunction. However, evidence supporting blood-based priming in contemporary LVAD surgery remains limited.