"Local injection of freshly collected autologous adipose tissue as a novel adjunctive treatment in hidradenitis suppurativa".

Dyneins are large ATP-dependent motor protein complexes first discovered for their role in driving flagellar movement in (Gibbons and Rowe ). They are classified into two main categories: axonemal dyneins, which are anchored on doublet microtubules within cilia and function as molecular engines for ciliary beating (Walton et al. ), and cytoplasmic dyneins (hereafter referred to as dyneins), which move along microtubules and are responsible for the retrograde transport of various cellular components (Reck-Peterson et al. ; Roberts ). Dynein-1 powers the minus-end-directed transport of various cargos within the cytoplasm, including membrane-bound organelles, protein complexes, RNAs, and viruses (Reck-Peterson et al. ). Dynein-2 is a ubiquitous motor responsible for retrograde intraflagellar transport (IFT) within the flagella and cilia (Roberts ). As such, dynein plays critical roles in mitosis, nuclear migration, organelle positioning, vesicle trafficking, misfolded protein clearance, and intercellular signaling (Eschbach and Dupuis ; Karki and Holzbaur ; Merdes et al. ). Ocular degenerative diseases are the major blinding ophthalmic disorders worldwide, mainly including glaucoma, aged-related macular degeneration, retinitis pigmentosa, and diabetic retinopathy. While these diseases may have distinct etiologies and pathogenesis, they are all characterized by the progressive loss of photoreceptor cell (PRC) or retinal ganglion cell (RGC), which may be triggered by a combination of genetic, environmental, and aging factors (Wang and Cepko ; Cuenca et al. ).