Effects of SGLT2 inhibitors on body composition and potential sarcopenia-related outcomes in type 2 diabetes mellitus: a network meta-analysis.

Asthma is a complex and heterogeneous condition characterized by chronic inflammation of the airways, which is responsible for bronchial hyperreactivity. Extensive research is constantly being published on the pathogenesis of the disease, diagnostic evaluation, phenotyping, and personalized therapy. Epidemiological data showed, by the end of the last century, an increasing prevalence of allergic diseases, including asthma []. Recently, a downward trend in the global burden of the disease over the past 30 years has been reported []. The global prevalence of asthma reported in 2020 was 9.1% among children and 11% among adolescents, while adults had a lower prevalence of 6.6% []. The mortality rate declined from 1990 to 2019, reaching 13.2% of deaths among children with asthma aged five to nine in the U.S. and 16.4% in the 10–14 age group []. Most cases begin in childhood. Approximately half of children with asthma still have poorly or partially controlled symptoms, even in some low- and middle-income countries. This may be due to limited access to essential asthma medications. Any regional or global strategy aimed at improving disease control and even achieving remission is welcome. Asthma is a relatively common chronic condition in childhood, but concerns regarding its prevention are much more limited compared to other chronic diseases, especially oncological pathology, including leukemia []. In the current era, there is a continuous need for changing health policies, promoting healthy lifestyle habits that include a healthy diet and regular physical exercise.